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Summary Expression Phenotypes Gene Literature (47) GO Terms (6) Nucleotides (379) Proteins (60) Interactants (657) Wiki

hspa5     heat shock protein family A (Hsp70) member 5

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal development of optic tectum (1 source), abnormally decreased number of neuron (1 source), abnormally increased number of neural progenitor cell (1 source), decreased cell population proliferation in neural progenitor cell (1 source), decreased cell population proliferation in optic tectum (1 source), decreased neuron differentiation in optic tectum (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: hspa5 assayed (1 source)
Computed annotations: hspa5 assayed (3 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + hspa5 MO (7 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (41 sources): abnormal alveolar lamellar body morphology, abnormal axon extension, abnormal axon fasciculation, abnormal axon morphology, abnormal blastocyst morphology, abnormal brain internal capsule morphology, abnormal brain white matter morphology, abnormal cerebral cortex morphology, abnormal circulating cholesterol level, abnormal cortical intermediate zone morphology, [+]