casp3.2 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-479959

Gene Symbol: casp3.2 Gene Name: caspase 3, gene 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: casp3.2 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (64 sources): abnormal apoptosis, abnormal auditory brainstem response waveform shape, abnormal bone marrow development, abnormal bone remodeling, abnormal cerebellar granule layer morphology, abnormal cerebellar molecular layer, abnormal cerebellum development, abnormal cerebellum external granule cell layer morphology, abnormal cochlear hair cell morphology, abnormal diencephalon morphology, abnormal ear morphology, abnormal eye development, abnormal granulosa cell morphology, abnormal keratinocyte physiology, abnormal lens development, abnormal lens epithelium morphology, abnormal olfactory bulb development, abnormal olfactory sensory neuron morphology, abnormal optic stalk morphology, abnormal organ of Corti morphology, abnormal osteoclast physiology, abnormal outer hair cell stereociliary bundle morphology, abnormal ovarian follicle morphology, abnormal retina inner nuclear layer morphology, abnormal retina pigment epithelium morphology, abnormal sagittal suture morphology, abnormal skeleton development, absent distortion product otoacoustic emissions, absent pinna reflex, absent startle reflex, cellular phenotype, cochlear ganglion degeneration, cochlear hair cell degeneration, cochlear inner hair cell degeneration, cochlear outer hair cell degeneration, cranial bossing, cranioschisis, deafness, decreased apoptosis, decreased body size, decreased fibroblast apoptosis, decreased keratinocyte apoptosis, decreased neuron apoptosis, decreased physiological sensitivity to xenobiotic, decreased sensitivity to induced cell death, decreased thymocyte number, decreased trabecular bone thickness, delayed bone ossification, fused outer hair cell stereocilia, hearing/vestibular/ear phenotype, immune system phenotype, increased cardiomyocyte apoptosis, increased cellular sensitivity to ultraviolet irradiation, increased or absent threshold for auditory brainstem response, increased sensitivity to induced cell death, nervous system phenotype, perinatal lethality, incomplete penetrance, postnatal lethality, complete penetrance, premature death, prenatal lethality, incomplete penetrance, renal/urinary system phenotype, reproductive system phenotype, respiratory system phenotype, vision/eye phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (64 sources): abnormal apoptosis, abnormal auditory brainstem response waveform shape, abnormal bone marrow development, abnormal bone remodeling, abnormal cerebellar granule layer morphology, abnormal cerebellar molecular layer, abnormal cerebellum development, abnormal cerebellum external granule cell layer morphology, abnormal cochlear hair cell morphology, abnormal diencephalon morphology, [+]