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Summary Expression Phenotypes Gene Literature (24) GO Terms (6) Nucleotides (125) Proteins (43) Interactants (375) Wiki

spib     Spi-B transcription factor

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal development of myeloid cell (2 sources), abnormally decreased number of myeloid cell (2 sources), abnormal myeloid cell morphology (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: spib manipulated (46 sources), spib assayed (13 sources)
Computed annotations: spib assayed (4 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + spib MO (12 sources), Xla Wt + spib MO (12 sources), Xla Wt + spib MO (11 sources), Xla Wt + spib MO (7 sources), Xla Wt + spib MO (7 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (12 sources): abnormal Peyer's patch morphology, abnormal humoral immune response, abnormal immature B cell morphology, abnormal spleen B cell follicle morphology, abnormal spleen germinal center morphology, abnormal spleen white pulp morphology, decreased B cell proliferation, decreased IgG1 level, decreased IgG2a level, decreased IgG2b level, [+]