| Monarch Ortholog Phenotypes
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Human (1 source):
Cleft palate
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Mouse (24 sources):
abnormal allantois morphology,
abnormal cell death,
abnormal common myeloid progenitor cell morphology,
abnormal dorsal aorta morphology,
abnormal embryonic hematopoiesis,
abnormal megakaryocyte progenitor cell morphology,
absent visceral yolk sac blood islands,
decreased embryo size,
decreased erythrocyte cell number,
decreased granulocyte number,
decreased hemoglobin content,
delayed embryo turning,
delayed somite formation,
distended pericardium,
embryonic lethality during organogenesis, complete penetrance,
enlarged thymus,
hematopoietic system phenotype,
immune system phenotype,
increased acute lymphoblastic leukemia incidence,
pale yolk sac,
premature death,
prenatal lethality,
short rostral-caudal axis,
small visceral yolk sac
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.