nkx3-1 Phenotypes

Phenotypes

XB-GENEPAGE-479026

Gene Symbol: nkx3-1 Gene Name: NK3 homeobox 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: nkx3-1 assayed (8 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (33 sources): abnormal bulbourethral gland development, abnormal bulbourethral gland morphology, abnormal bulbourethral gland physiology, abnormal minor salivary gland morphology, abnormal palatine gland morphology, abnormal prostate gland anterior lobe morphology, abnormal prostate gland branching morphogenesis, abnormal prostate gland epithelium morphology, abnormal prostate gland morphology, abnormal prostate gland physiology, abnormal salivary gland duct morphology, bulbourethral gland hypoplasia, decreased ductal branching in the coagulating gland, decreased ductal branching in the palatine gland, decreased prostate gland duct number, decreased salivation, embryo phenotype, increased cell proliferation, increased prostate intraepithelial neoplasia incidence, increased salivary gland mucosal cell number, narrow salivary ducts, preneoplasia, prostate gland anterior lobe hyperplasia, prostate gland epithelial hyperplasia, prostate gland lateral lobe hypoplasia, reduced male mating frequency, reproductive system phenotype, salivary gland epithelial hyperplasia, small bulbourethral gland, small prostate gland anterior lobe, small prostate gland ventral lobe, small salivary gland, small seminal vesicle [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (33 sources): abnormal bulbourethral gland development, abnormal bulbourethral gland morphology, abnormal bulbourethral gland physiology, abnormal minor salivary gland morphology, abnormal palatine gland morphology, abnormal prostate gland anterior lobe morphology, abnormal prostate gland branching morphogenesis, abnormal prostate gland epithelium morphology, abnormal prostate gland morphology, abnormal prostate gland physiology, [+]