Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (15) GO Terms (8) Nucleotides (125) Proteins (51) Interactants (303) Wiki
XB-GENEPAGE-478812

fzd6     frizzled class receptor 6

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal head morphology (2 sources), abnormal tail bud morphology (2 sources), decreased length of anterior-posterior axis (2 sources), abnormal gastrulation (1 source), abnormal neural tube closure (1 source), abnormally delayed closure of blastopore (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: fzd6 assayed (9 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + fzd6 MO (3 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (6 sources): Nail dysplasia, Onychauxis, Onychogryposis, Onycholysis, Thin nail, Trachyonychia
Mouse (5 sources): abnormal circulating alkaline phosphatase level, abnormal hair follicle orientation, decreased red blood cell distribution width, increased circulating alkaline phosphatase level, no abnormal phenotype detected

View all ortholog results at Monarch