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Summary Expression Phenotypes Gene Literature (141) GO Terms (19) Nucleotides (417) Proteins (67) Interactants (900) Wiki

fgfr1     fibroblast growth factor receptor 1

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal tadpole morphology (6 sources), decreased size of the tail (4 sources), decreased size of the trunk (4 sources), decreased size of the muscle (2 sources), abnormal foregut (1 source), abnormal protein phosphorylation (1 source), absent foregut (1 source), decreased size of the liver primordium (1 source), decreased size of the lung primordium (1 source), increased MAP kinase activity (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: fgfr1 manipulated (13 sources), fgfr1 assayed (1 source)
Computed annotations: fgfr1 assayed (9 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + fgfr1scFv_A2 (4 sources), Xla Wt + Mmu.fgfr1del-Mmu.fkbp1adel + B/B Homodimerizer (4 sources), Xla Wt + fgfr1 (3 sources), Xla Wt + Mmu.fgfr1del-Mmu.fkbp1adel + wnt2 MO + B/B Homodimerizer (3 sources), Xla Wt + dnfgfr1 (3 sources), Xla Wt + dnfgfr1 (2 sources), Xla Wt + dnfgfr1 (2 sources), Xla Wt + fgfr1scFv_A23 (1 source), Xla Wt + fgfr1scFv_A2 (1 source), Xla Wt + fgfr1scFv_A7 (1 source), Xla Wt + fgfr1scFv_C3 (1 source), Xla Wt + Mmu.fgfr1del-Mmu.fkbp1adel + B/B Homodimerizer (1 source), Xla Wt + dnfgfr1 (1 source), Xla Wt + dnfgfr1 (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (302 sources): 2-3 toe syndactyly, Abnormal anterior chamber morphology, Abnormal aortic morphology, Abnormal bone ossification, Abnormal cartilage morphology, Abnormal clavicle morphology, Abnormal eyelash morphology, Abnormal eyelid morphology, Abnormal form of the vertebral bodies, Abnormal morphology of female internal genitalia, [+]
Mouse (198 sources): abnormal alisphenoid bone morphology, abnormal apical ectodermal ridge morphology, abnormal astrocyte morphology, abnormal auditory bulla morphology, abnormal axon guidance, abnormal basisphenoid bone morphology, abnormal blastocyst morphology, abnormal brain commissure morphology, abnormal cartilage development, abnormal cerebellum development, [+]

View all ortholog results at Monarch