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Summary Expression Phenotypes Gene Literature (43) GO Terms (3) Nucleotides (133) Proteins (53) Interactants (609) Wiki

tbx3     T-box 3

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal gastrulation (2 sources), abnormal axis elongation (1 source), abnormal bending of tail (1 source), abnormal tail morphology (1 source), abnormally delayed closure of blastopore (1 source), absent head (1 source), absent tail (1 source), decreased length of anterior-posterior axis (1 source), decreased size of the head (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: tbx3 assayed (1 source)
Computed annotations: tbx3 assayed (17 sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + tbx3 MO (2 sources), Xtr Wt + tbx3 MO (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (58 sources): Abnormal clavicle morphology, Abnormal fingernail morphology, Abnormality of finger, Abnormality of temperature regulation, Abnormality of the humerus, Abnormality of the metacarpal bones, Abnormality of the radius, Abnormality of the uterus, Abnormality of the wrist, Absent axillary hair, [+]
Mouse (52 sources): abnormal P wave, abnormal QRS complex, abnormal cardiovascular development, abnormal clitoris morphology, abnormal embryonic autopod plate morphology, abnormal female reproductive system morphology, abnormal fetal atrioventricular canal morphology, abnormal forelimb morphology, abnormal heart development, abnormal heart looping, [+]

View all ortholog results at Monarch