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XB-GENEPAGE-1017460
dvl2 dishevelled segment polarity protein 2
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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abnormally increased number of multiciliated cell (2 sources), absent epidermis outer layer (2 sources), absent multiciliated cell (2 sources), decreased length of anterior-posterior axis (2 sources), increased thickness of the ectoderm (2 sources), abnormal bending of anterior-posterior axis (1 source), abnormal cell migration (1 source), abnormal development of hindgut (1 source), abnormal gastrulation (1 source), abnormal incomplete closing of the neural fold (1 source), abnormal incomplete closing of the neural tube (1 source), abnormal neural tube closure (1 source), abnormal neural tube morphology (1 source), abnormal retina (1 source), abnormally decreased length of hindgut (1 source), increased size of the foregut (1 source), obsolete duplicated anterior-posterior axis (1 source) |
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Manual annotations: dvl2 manipulated (6 sources) |
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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Xla Wt + dndvl2 (3 sources), Xla Wt + dndvl2-GFP (3 sources), Xla Wt + dndvl2-GFP (2 sources), Xla Wt + dndvl2-GFP + sfrp5 MO (2 sources), Xla Wt + dvl2 (1 source), Xla Wt + dvl2 MO (1 source), Xla Wt + dvl2 MO + dvl3 MO (1 source), Xla Wt + dvl2del_1236-2208 (1 source), Xla Wt + dvl2del_1236-2208 (1 source), Xla Wt + dndvl2 (1 source), Xla Wt + dndvl2 (1 source), Xla Wt + dndvl2 + cdh2 MO (1 source) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Mouse (9 sources): abnormal somite development, abnormal thoracic vertebrae morphology, abnormal xiphoid process morphology, hearing/vestibular/ear phenotype, kinked tail, open neural tube, perinatal lethality, incomplete penetrance, short hair, vestigial tail |