abnormal myocardium layer morphology, abnormal nucleated erythrocyte cell number, abnormal placenta labyrinth morphology, abnormal placenta morphology, abnormal renal glomerulus morphology, abnormal response of heart to induced stress, abnormal response to cardiac infarction, abnormal splenic cell ratio, abnormal spongiotrophoblast layer morphology, abnormal trabecula carnea morphology, abnormal trophoblast giant cell morphology, blood vessel congestion, cardiac interstitial fibrosis, cardiac ischemia, cardiovascular system phenotype, decreased body size, decreased cardiomyocyte apoptosis, decreased myocardial infarct size, decreased survivor rate, decreased trophoblast giant cell number, decreased ventricle muscle contractility, dilated liver sinusoidal spaces, dilated vasculature, embryonic lethality during organogenesis, complete penetrance, enlarged heart atrium, enlarged myocardial fiber, hematopoietic system phenotype, increased angiogenesis, increased circulating erythropoietin level, increased erythroblast number, increased erythropoietin level, increased heart weight, increased liver weight, increased pulmonary ventilation, increased response of heart to induced stress, increased spleen weight, increased tidal volume, lethality during fetal growth through weaning, complete penetrance, liver vascular congestion, muscle phenotype, myocardial fiber degeneration, pale yolk sac, premature death, prenatal lethality, complete penetrance, preweaning lethality, complete penetrance, pulmonary vascular congestion, thin myocardium compact layer