Monarch Ortholog Phenotypes
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Human (9 sources):
Abnormality of coagulation,
Dandy-Walker malformation,
Elevated circulating creatine kinase concentration,
Generalized hypotonia,
Global developmental delay,
Hydrocephalus,
Hypotonia,
Macrocephaly,
Myopathy
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Mouse (54 sources):
abnormal Paneth cell morphology,
abnormal adenohypophysis development,
abnormal adrenal cortex morphology,
abnormal adrenal gland zona fasciculata morphology,
abnormal adrenal gland zona reticularis morphology,
abnormal branching of the mammary ductal tree,
abnormal epidermis stratum corneum morphology,
abnormal epidermis stratum granulosum morphology,
abnormal epidermis stratum spinosum morphology,
abnormal glomerular mesangium morphology,
abnormal gut flora balance,
abnormal intestinal epithelium morphology,
abnormal leukocyte physiology,
abnormal mammary gland growth during pregnancy,
abnormal milk composition,
abnormal physiological neovascularization,
abnormal proerythroblast morphology,
abnormal pulmonary alveolar system morphology,
abnormal pulmonary alveolus morphology,
abnormal renal glomerulus morphology,
abnormal small intestine crypts of Lieberkuhn morphology,
abnormal sperm physiology,
acanthosis,
decreased acute inflammation,
decreased circulating interleukin-6 level,
decreased circulating thyroxine level,
decreased erythrocyte cell number,
decreased hair follicle number,
decreased hematocrit,
decreased hemoglobin content,
decreased litter size,
decreased sensitivity to induced morbidity/mortality,
decreased susceptibility to induced colitis,
decreased susceptibility to type IV hypersensitivity reaction,
delayed wound healing,
digestive/alimentary phenotype,
dystocia,
hematopoietic system phenotype,
homeostasis/metabolism phenotype,
impaired acrosome reaction,
impaired macrophage chemotaxis,
impaired neutrophil recruitment,
increased mitotic index,
increased neutrophil cell number,
lactation failure,
long gestation period,
neonatal lethality, incomplete penetrance,
postnatal lethality, incomplete penetrance,
premature death,
skin lesions,
small adenohypophysis,
small adrenal glands,
small seminiferous tubules,
thick pulmonary interalveolar septum
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View all ortholog results at Monarch
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