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Summary Expression Phenotypes Gene Literature (6) GO Terms (7) Nucleotides (60) Proteins (38) Interactants (44) Wiki
XB-GENEPAGE-1013732

irf3     interferon regulatory factor 3

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: irf3 assayed (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (15 sources): abnormal circulating interferon level, abnormal kidney morphology, abnormal retina outer nuclear layer morphology, abnormal retina outer plexiform layer morphology, decreased a-wave amplitude, decreased b-wave amplitude, decreased cellular sensitivity to ultraviolet irradiation, decreased total retina thickness, enlarged lymph nodes, increased susceptibility to Picornaviridae infection, [+]