ophn1 Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (139)

Interactants (24)

XB-GENEPAGE-1009724

Gene Symbol: ophn1 Gene Name: oligophrenin 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ophn1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (40 sources): Abnormal facial shape, Abnormality of the philtrum, Ataxia, Attention deficit hyperactivity disorder, Autism, Cerebellar hypoplasia, Cerebral cortical atrophy, Cryptorchidism, Deeply set eye, Delayed speech and language development, Disorganization of the anterior cerebellar vermis, Dysmetria, Enlarged cisterna magna, Frontal bossing, Gait ataxia, Generalized hypotonia, Global developmental delay, Hyperactivity, Hypotelorism, Hypotonia, Intellectual disability, Long face, Long nose, Macrocephaly, Macrotia, Mandibular prognathia, Micropenis, Microphallus, Neurological speech impairment, Nystagmus, Prominent forehead, Prominent supraorbital ridges, Retrocerebellar cyst, Seizure, Short philtrum, Small scrotum, Spasticity, Strabismus, Thin upper lip vermilion, Ventriculomegaly [+]
Mouse (19 sources): abnormal aggression-related behavior, abnormal dendrite morphology, abnormal excitatory postsynaptic potential, abnormal response to novelty, abnormal spatial learning, abnormal zigzag hair morphology, asthenozoospermia, curly vibrissae, decreased aggression towards mice, decreased anxiety-related response, decreased body size, decreased litter size, increased brain size, increased exploration in new environment, increased thigmotaxis, premature death, preweaning lethality, incomplete penetrance, thin cerebral cortex, transverse fur striping [+]
View all ortholog results at Monarch