| Monarch Ortholog Phenotypes
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Human (26 sources):
Abnormal bleeding,
Anemia,
Bruising susceptibility,
Decreased platelet glycoprotein IIb-IIIa,
Ecchymosis,
Epistaxis,
Gastrointestinal hemorrhage,
Giant platelets,
Gingival bleeding,
Impaired clot retraction,
Impaired platelet aggregation,
Impaired ristocetin-induced platelet aggregation,
Intracranial hemorrhage,
Macroscopic hematuria,
Macrothrombocytopenia,
Menometrorrhagia,
Menorrhagia,
Petechiae,
Platelet anisocytosis,
Prolonged bleeding after surgery,
Prolonged bleeding following circumcision,
Prolonged bleeding time,
Purpura,
Spontaneous hematomas,
Spontaneous, recurrent epistaxis,
Thrombocytopenia
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Mouse (11 sources):
abnormal blood coagulation,
abnormal cell adhesion,
abnormal definitive hematopoiesis,
abnormal embryonic hematopoiesis,
abnormal hemostasis,
abnormal platelet activation,
abnormal platelet alpha-granule morphology,
decreased erythrocyte cell number,
increased hematopoietic stem cell number,
reproductive system phenotype,
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.