clp1 Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (164)

Interactants (19)

XB-GENEPAGE-1008969

Gene Symbol: clp1 Gene Name: cleavage factor polyribonucleotide kinase subunit 1

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (43 sources): Abnormal brainstem morphology, Abnormal cerebral cortex morphology, Abnormal cerebral white matter morphology, Absent speech, Cerebral cortical atrophy, Cryptorchidism, Delayed fine motor development, Delayed gross motor development, Delayed myelination, Delayed speech and language development, Encephalopathy, Esotropia, Generalized hypotonia, Global developmental delay, Growth delay, High palate, Highly arched eyebrow, Hyperreflexia, Hypoplasia of the corpus callosum, Intellectual disability, Irritability, Kyphoscoliosis, Long eyelashes, Long palpebral fissure, Microcephaly, Nystagmus, Optic atrophy, Poor eye contact, Poor head control, Progressive microcephaly, Proptosis, Seizure, Sensorimotor neuropathy, Short nose, Simplified gyral pattern, Spasticity, Strabismus, Thin upper lip vermilion, Underdeveloped nasal alae, Ventriculomegaly, Visual fixation instability, Visual impairment, Wide nasal bridge [+]
Mouse (25 sources): abnormal axon morphology, abnormal microglial cell morphology, abnormal neuromuscular synapse morphology, abnormal phrenic nerve innervation pattern to diaphragm, abnormal sciatic nerve morphology, behavior/neurological phenotype, decreased birth weight, decreased brain size, decreased brain weight, decreased motor neuron number, decreased neuron number, defasiculated phrenic nerve, embryonic lethality, complete penetrance, hyporesponsive to tactile stimuli, impaired balance, increased cellular sensitivity to oxidative stress, increased neuron apoptosis, lethality, complete penetrance, maternal effect, neonatal lethality, complete penetrance, nervous system phenotype, oxidative stress, premature death, respiratory system phenotype, thin cerebral cortex [+]
View all ortholog results at Monarch