| Monarch Ortholog Phenotypes
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Human (27 sources):
Absent scrotum,
Aggressive behavior,
Anteverted nares,
Buphthalmos,
Cerebellar hypoplasia,
Dandy-Walker malformation,
Gait ataxia,
Hirsutism,
Horizontal nystagmus,
Hyperactive deep tendon reflexes,
Hypoplasia of the pons,
Keratoconjunctivitis sicca,
Laterally extended eyebrow,
Long eyelashes,
Long philtrum,
Low anterior hairline,
Low-set ears,
Microcephaly,
Posteriorly rotated ears,
Protruding ear,
Retinal degeneration,
Smooth philtrum,
Strabismus,
Synophrys,
Tented philtrum,
Visual impairment,
Wide intermamillary distance
[+]
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Mouse (10 sources):
abnormal male preputial gland morphology,
abnormal optic placode morphology,
abnormal retina pigment epithelium morphology,
absent ciliary body,
absent lens vesicle,
aphakia,
decreased retina inner nuclear layer thickness,
increased total retina thickness,
small male preputial glands,
thin retina outer nuclear layer
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.