Monarch Ortholog Phenotypes
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Mouse (30 sources):
abnormal atrioventricular valve morphology,
abnormal cranium morphology,
abnormal heart shape,
abnormal lens fiber morphology,
abnormal mitral valve morphology,
abnormal pulmonary alveolus morphology,
abnormal retina ganglion layer morphology,
abnormal retina inner nuclear layer morphology,
abnormal retina layer morphology,
abnormal skeleton development,
cardiac hypertrophy,
decreased body length,
decreased body size,
decreased cranium height,
decreased pancreas weight,
decreased retina inner nuclear layer thickness,
decreased total retina thickness,
domed cranium,
improved glucose tolerance,
increased heart weight,
increased liver weight,
increased lung weight,
increased ovary weight,
increased spleen weight,
no abnormal phenotype detected,
overexpanded pulmonary alveoli,
postnatal lethality, incomplete penetrance,
pulmonary alveolar hemorrhage,
slow postnatal weight gain,
thick pulmonary interalveolar septum
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