Monarch Ortholog Phenotypes
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Mouse (36 sources):
abnormal GABA-mediated receptor currents,
abnormal GABAergic neuron morphology,
abnormal GABAergic neuron physiology,
abnormal airway basal cell differentiation,
abnormal brain interneuron morphology,
abnormal cerebral cortex morphology,
abnormal cerebral cortex pyramidal cell morphology,
abnormal circulating cholesterol level,
abnormal interleukin level,
abnormal myeloblast morphology/development,
abnormal nicotine-mediated receptor currents,
abnormal seizure response to pharmacological agent,
abnormal somatosensory cortex morphology,
abnormal spatial learning,
abnormal spatial working memory,
abnormal suckling behavior,
abnormal tumor necrosis factor level,
airway basal cell hyperplasia,
asthenozoospermia,
behavior/neurological phenotype,
decreased CNS synapse formation,
decreased anxiety-related response,
decreased erythroblast number,
decreased litter size,
decreased locomotor activity,
failure of neuromuscular synapse presynaptic differentiation,
immune system phenotype,
impaired olfaction,
increased neuron apoptosis,
neonatal lethality, complete penetrance,
nervous system phenotype,
no abnormal phenotype detected,
prolonged estrous cycle,
reduced female fertility,
reduced fertility,
reproductive system phenotype
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