eif2b5 Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (117)

Interactants (30)

XB-GENEPAGE-986285

Gene Symbol: eif2b5 Gene Name: eukaryotic translation initiation factor 2B subunit epsilon

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (27 sources): Blindness, CNS demyelination, Cerebral hypomyelination, Cessation of head growth, Decreased circulating progesterone, Delusions, Developmental regression, Dysarthria, Emotional lability, Fever, Gait disturbance, Generalized hypotonia, Gliosis, Hypotonia, Lethargy, Leukoencephalopathy, Macrocephaly, Memory impairment, Optic atrophy, Personality changes, Premature ovarian insufficiency, Primary amenorrhea, Primary gonadal insufficiency, Secondary amenorrhea, Seizure, Spasticity, Unsteady gait [+]
Mouse (25 sources): abnormal astrocyte morphology, abnormal astrocyte physiology, abnormal axon morphology, abnormal brain internal capsule morphology, abnormal brain white matter morphology, abnormal cerebellum white matter morphology, abnormal locomotor activation, abnormal microglial cell physiology, abnormal physiological response to xenobiotic, abnormal retina inner nuclear layer morphology, abnormal retina outer nuclear layer morphology, brain vacuoles, decreased circulating glucose level, decreased grip strength, decreased heart weight, decreased mean corpuscular hemoglobin concentration, decreased mean corpuscular volume, decreased oligodendrocyte number, decreased percent body fat/body weight, ectopic Bergmann glia cells, increased oligodendrocyte number, premature death, slow postnatal weight gain, sporadic seizures, thin retina inner plexiform layer [+]
View all ortholog results at Monarch