Monarch Ortholog Phenotypes
|
Human (20 sources):
Acute kidney injury,
Chronic kidney disease,
Decreased circulating complement factor H concentration,
Depletion of components of the alternative complement pathway,
Drusen,
Glomerular subendothelial electron-dense deposits,
Glomerulonephritis,
Hematuria,
Hemolytic anemia,
Hemolytic-uremic syndrome,
[+]
|
Mouse (48 sources):
abnormal Bruch membrane morphology,
abnormal blood coagulation,
abnormal blood homeostasis,
abnormal brain thrombosis,
abnormal circulating complement protein level,
abnormal complement protein level,
abnormal glomerular capillary endothelium morphology,
abnormal glomerular capillary morphology,
abnormal glomerular capillary thrombosis,
abnormal glomerular mesangium morphology,
abnormal hepatic portal vein thrombosis,
abnormal kidney blood vessel morphology,
abnormal kidney capillary morphology,
abnormal kidney morphology,
abnormal kidney thrombosis,
abnormal kidney venous thrombosis,
abnormal lung thrombosis,
abnormal renal glomerulus basement membrane morphology,
abnormal renal glomerulus morphology,
abnormal retina layer morphology,
abnormal retina photoreceptor morphology,
abnormal retina pigment epithelium morphology,
abnormal retina rod bipolar cell morphology,
abnormal retina vasculature morphology,
abnormal thrombosis,
amyloid beta deposits,
artery occlusion,
brain ischemia,
circling,
decreased a-wave amplitude,
decreased b-wave amplitude,
decreased body size,
decreased circulating complement protein level,
decreased complement C5 level,
decreased hemoglobin content,
decreased serum complement activity,
decreased visual acuity,
disorganized photoreceptor outer segment,
hindlimb paralysis,
increased creatine level,
increased mean corpuscular hemoglobin,
increased mesangial cell number,
increased susceptibility to type III hypersensitivity reaction,
increased susceptilbility to retina ischemic injury,
mesangial cell interposition,
premature death,
renal glomerular immunoglobulin deposits,
renal glomerular protein deposits
[+]
|
View all ortholog results at Monarch
|