| Monarch Ortholog Phenotypes
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Human (17 sources):
Angina pectoris,
Atherosclerosis,
Corneal opacity,
Decreased HDL cholesterol concentration,
Foam cells,
Hemolytic anemia,
Hepatomegaly,
Hypertriglyceridemia,
Increased LDL cholesterol concentration,
Increased VLDL cholesterol concentration,
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Mouse (13 sources):
abnormal kidney afferent arteriole morphology,
abnormal lipid homeostasis,
abnormal lipid level,
abnormal renal glomerulus morphology,
decreased cholesterol level,
decreased erythrocyte osmotic fragility,
hematopoietic system phenotype,
homeostasis/metabolism phenotype,
increased cholesterol level,
increased circulating phospholipid level,
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.