Monarch Ortholog Phenotypes
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Mouse (22 sources):
abnormal embryo size,
abnormal excitatory postsynaptic potential,
abnormal hippocampus neuron morphology,
abnormal learning/memory/conditioning,
abnormal neuron differentiation,
abnormal neuron proliferation,
abnormal passive avoidance behavior,
behavior/neurological phenotype,
decreased birth weight,
decreased locomotor activity,
embryonic lethality, complete penetrance,
impaired cued conditioning behavior,
impaired spatial learning,
increased anxiety-related response,
increased kidney weight,
increased liver weight,
kidney epithelium hyperplasia,
persistence of hyaloid vascular system,
postnatal lethality, complete penetrance,
preweaning lethality, complete penetrance,
reduced long term potentiation,
slow postnatal weight gain
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