Monarch Ortholog Phenotypes
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Mouse (38 sources):
abnormal cranium morphology,
abnormal intercalated disk morphology,
abnormal intestinal absorption,
abnormal myocardial fiber morphology,
abnormal myocardial fiber physiology,
abnormal spermatid morphology,
abnormal testis development,
abnormal vascular regression,
abnormal white adipose tissue physiology,
decreased abdominal adipose tissue amount,
decreased body length,
decreased brown fat cell size,
decreased cardiac muscle contractility,
decreased circulating glucose level,
decreased core body temperature,
decreased litter size,
decreased male germ cell number,
decreased susceptibility to diet-induced obesity,
decreased white adipose tissue amount,
decreased white fat cell size,
embryonic growth arrest,
impaired adaptive thermogenesis,
increased basal metabolism,
increased brain size,
increased brain weight,
increased heart weight,
increased kidney weight,
increased startle reflex,
lethality throughout fetal growth and development, complete penetrance,
lethality throughout fetal growth and development, incomplete penetrance,
poor grooming,
premature death,
reduced fertility,
reduced male fertility,
skin edema,
slow postnatal weight gain,
thin myocardium,
ventricle myocardium hypoplasia
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