pthlh Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (56)

Interactants (2)

XB-GENEPAGE-959053

Gene Symbol: pthlh Gene Name: parathyroid hormone-like hormone

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pthlh assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (13 sources): Aplasia/Hypoplasia of the distal phalanx of the hallux, Brachydactyly, Delayed eruption of teeth, Frontal bossing, Macrocephaly, Oligodontia, Short distal phalanx of finger, Short metacarpal, Short metatarsal, Short stature, Type E brachydactyly, Upper limb asymmetry, obsolete Joint hyperflexibility [+]
Mouse (77 sources): abnormal autophagy, abnormal blood urea nitrogen level, abnormal bone mineralization, abnormal brain vasculature morphology, abnormal calcium ion homeostasis, abnormal cartilage development, abnormal cervical rib, abnormal circulating calcium level, abnormal clavicle morphology, abnormal cranium morphology, abnormal ductus venosus valve morphology, abnormal long bone epiphyseal plate morphology, abnormal long bone epiphyseal plate proliferative zone, abnormal long bone hypertrophic chondrocyte zone, abnormal long bone metaphysis morphology, abnormal lung development, abnormal lung interstitium morphology, abnormal lung saccule morphology, abnormal mandible morphology, abnormal mesenchymal cell differentiation involved in lung development, abnormal osteoblast differentiation, abnormal osteoblast morphology, abnormal osteoclast morphology, abnormal pulmonary alveolus epithelium morphology, abnormal skeleton development, abnormal sternum ossification, abnormal thoracic cage shape, abnormal type II pneumocyte morphology, abnormal vertebral body morphology, abnormal vitamin D level, absent type I pneumocytes, chondrodystrophy, decreased alveolar lamellar body number, decreased body size, decreased brain size, decreased cell proliferation, decreased chondrocyte number, decreased chondrocyte proliferation, decreased circulating glucose level, decreased circulating iron level, decreased long bone epiphyseal plate size, decreased osteoblast cell number, decreased osteoclast cell number, decreased surfactant secretion, dilated liver sinusoidal spaces, disorganized long bone epiphyseal plate, disproportionate dwarf, domed cranium, embryo tumor, growth/size/body region phenotype, increased apoptosis, increased bone mass, increased chondrocyte apoptosis, increased compact bone thickness, increased diameter of long bones, increased osteoblast apoptosis, increased osteoblast cell number, increased osteocyte apoptosis, increased width of hypertrophic chondrocyte zone, neonatal lethality, complete penetrance, no abnormal phenotype detected, perinatal lethality, complete penetrance, postnatal lethality, complete penetrance, premature aging, premature bone ossification, premature endochondral bone ossification, preweaning lethality, complete penetrance, reproductive system phenotype, short mandible, short radius, skeleton phenotype, small lung, small lung saccule, small thoracic cavity, splayed ribs, thick lung-associated mesenchyme, thin epidermis [+]
View all ortholog results at Monarch