tmod1 Phenotypes

Phenotypes

XB-GENEPAGE-954353

Gene Symbol: tmod1 Gene Name: tropomodulin 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tmod1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (37 sources): abnormal atrial thrombosis, abnormal cardiac muscle contractility, abnormal cardiac muscle relaxation, abnormal cardiac output, abnormal embryonic erythrocyte morphology, abnormal embryonic tissue morphology, abnormal fetal atrioventricular canal morphology, abnormal head development, abnormal heart development, abnormal heart looping, abnormal heart tube morphology, abnormal myocardial fiber morphology, abnormal sarcomere morphology, abnormal vascular development, abnormal vitelline vasculature morphology, absent heartbeat, absent myocardial trabeculae, decreased cardiac muscle contractility, decreased cardiac output, decreased embryo size, decreased ventricle muscle contractility, dilated heart left ventricle, distended pericardium, embryonic growth arrest, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, excessive folding of visceral yolk sac, increased circulating alkaline phosphatase level, increased heart weight, increased sensitivity to induced morbidity/mortality, lethality at weaning, incomplete penetrance, myocardial fiber degeneration, postnatal lethality, incomplete penetrance, premature death, respiratory system phenotype, thin interventricular septum, thin myocardium [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (37 sources): abnormal atrial thrombosis, abnormal cardiac muscle contractility, abnormal cardiac muscle relaxation, abnormal cardiac output, abnormal embryonic erythrocyte morphology, abnormal embryonic tissue morphology, abnormal fetal atrioventricular canal morphology, abnormal head development, abnormal heart development, abnormal heart looping, [+]