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Summary Expression Phenotypes Gene Literature (2) GO Terms (3) Nucleotides (76) Proteins (42) Interactants (2) Wiki
XB-GENEPAGE-952650

cln8     CLN8, transmembrane ER and ERGIC protein

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: cln8 assayed (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (20 sources): Ataxia, Atypical behavior, Bilateral tonic-clonic seizure, Cerebellar atrophy, Cerebral atrophy, Clumsiness, Curvilinear intracellular accumulation of autofluorescent lipopigment storage material, Delayed speech and language development, Developmental regression, EEG abnormality, [+]
Mouse (18 sources): abnormal heart weight, abnormal locomotor behavior, abnormal motor capabilities/coordination/movement, abnormal retina photoreceptor layer morphology, abnormal retina pigment epithelium morphology, abnormal retina rod cell inner segment morphology, abnormal retina rod cell outer segment morphology, abnormal spinal cord ventral horn morphology, abnormal vagus nerve morphology, decreased freezing behavior, [+]

View all ortholog results at Monarch