Monarch Ortholog Phenotypes
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Human (35 sources):
Aggressive behavior,
Agitation,
Ankle clonus,
Apathy,
Ataxia,
Babinski sign,
Brisk reflexes,
Cognitive impairment,
Degeneration of the lateral corticospinal tracts,
Dementia,
Depression,
Disinhibition,
Distal amyotrophy,
Dysarthria,
Functional motor deficit,
Hyperreflexia,
Hyperreflexia in upper limbs,
Impaired vibration sensation at ankles,
Impaired vibration sensation in the lower limbs,
Intellectual disability,
Leg muscle stiffness,
Low back pain,
Lower limb muscle weakness,
Lower limb spasticity,
Memory impairment,
Nystagmus,
Paraplegia,
Pes cavus,
Seizure,
Spastic gait,
Spastic paraplegia,
Spasticity,
Urinary bladder sphincter dysfunction,
Urinary incontinence,
Urinary urgency
[+]
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Mouse (5 sources):
abnormal axon morphology,
abnormal axonal transport,
long stride length,
no abnormal phenotype detected,
short stride length
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View all ortholog results at Monarch
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