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XB-GENEPAGE-946621
hif1a hypoxia inducible factor 1 subunit alpha
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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abnormal regenerating tail (2 sources), decreased length of regenerating tail (2 sources), abnormal Wnt signaling pathway (1 source), abnormal cranial neural crest morphology (1 source), abnormal neural plate morphology (1 source), decreased cell migration in branchial crest (1 source), decreased cell migration in cranial neural crest (1 source), decreased cell migration in hyoid crest (1 source), decreased cell migration in mandibular crest (1 source), decreased size of the main body axis (1 source) |
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Manual annotations: hif1a manipulated (1 source) |
Computed annotations: hif1a assayed (1 source) |
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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Xtr Wt + hif1a MO NF1 (2 sources), Xtr Wt + hif1a MO NF2 (1 source), Xtr Wt + hif1a vMO 20ng + posterior tail amputation (1 source), Xtr.Tg(pbin7:GFP) + hif1a MO (1 source) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Mouse (140 sources): abnormal T cell differentiation, abnormal angiogenesis, abnormal body temperature, abnormal brain vasculature morphology, abnormal cardiac muscle relaxation, abnormal cardiac outflow tract development, abnormal cartilage development, abnormal cerebral cortex morphology, abnormal cerebral hemisphere morphology, abnormal coronary vessel morphology, [+] |