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XB-GENEPAGE-946234
rspo2 R-spondin 2
Anatomical Phenotypes
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wholly ventralized embryo (4 sources), abnormal foregut morphology (1 source), abnormal gastrulation (1 source), abnormal heart (1 source), abnormal heart morphology (1 source), abnormally oblique orientation of heart (1 source) |
Expression Phenotypes
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Manual annotations: rspo2 manipulated (16 sources), rspo2 assayed (3 sources) |
Computed annotations: rspo2 assayed (22 sources) |
Diseases
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visceral heterotaxy (2AP sources, 2 EP sources) |
Experiments (Reagents)
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Xla Wt + rspo2 MO (3 sources), Xla Wt + rspo2 MO (2 sources), Xla Wt + rspo2 MO (2 sources), Xla Wt + rspo2 MO - left (2 sources), Xla Wt + rspo2 MO - right (2 sources), Xtr Wt + nog CRISPR + rspo2 CRISPR (2 sources), Xtr Wt + rspo2 CRISPR (2 sources), Xtr Wt + rspo2 CRISPR + chrd.1 CRISPR (2 sources), Xla Wt + bmp4 + rspo2 + animal cap explant (1 source), Xla Wt + bmpr1a + rspo2 (1 source), Xla Wt + bmpr1a + rspo2 MO + ventro-lateral marginal zone explant (1 source), Xla Wt + bmpr1a + rspo2 MO + ventro-lateral marginal zone explant (1 source), Xla Wt + rspo2 (1 source), Xla Wt + rspo2 MO (1 source) |
Monarch Ortholog Phenotypes
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Human (36 sources): Abnormal lung lobation, Abnormal rib morphology, Abnormality of the larynx, Abnormally ossified vertebrae, Agenesis of corpus callosum, Anal atresia, Ankyloglossia, Aplasia/Hypoplasia involving the nose, Aplasia/Hypoplasia involving the pelvis, Aplasia/Hypoplasia of the lungs, [+] |
Mouse (43 sources): abnormal apical ectodermal ridge morphology, abnormal digestive system development, abnormal forelimb morphology, abnormal forelimb zeugopod morphology, abnormal hindlimb morphology, abnormal kidney development, abnormal laryngeal cartilage morphology, abnormal limb development, abnormal limb morphology, abnormal lung vasculature morphology, [+] |
View all ortholog results at Monarch |