Monarch Ortholog Phenotypes
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Human (31 sources):
Abnormal foot morphology,
Abnormality of coordination,
Abnormality of eye movement,
Abnormality of the vasculature,
Ataxia,
Axial hypotonia,
Cognitive impairment,
Dysarthria,
Dysdiadochokinesis,
Dystonia,
Fatigue,
Gait disturbance,
Generalized hypotonia,
Global developmental delay,
Hyperhidrosis,
Hypomimic face,
Inappropriate crying,
Limb dystonia,
Nasal speech,
Oculogyric crisis,
Orofacial dyskinesia,
Parkinsonism,
Poor head control,
Ptosis,
Secondary microcephaly,
Shuffling gait,
Sleep disturbance,
Spastic tetraparesis,
Spasticity,
Stridor,
Tremor
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Mouse (48 sources):
abnormal associative learning,
abnormal circadian behavior,
abnormal corticosterone level,
abnormal dopamine level,
abnormal dopaminergic neuron morphology,
abnormal liquid preference,
abnormal motor capabilities/coordination/movement,
abnormal neurotransmitter secretion,
abnormal neurotransmitter uptake,
abnormal noradrenaline level,
abnormal response to new environment,
abnormal response to novel odor,
abnormal response to novelty,
abnormal serotonin level,
abnormal sleep pattern,
abnormal synaptic neurotransmitter level,
abnormal synaptic vesicle morphology,
absent gastric milk in neonates,
alpha-synuclein inclusion body,
behavior/neurological phenotype,
decreased alcohol consumption,
decreased anxiety-related response,
decreased birth body size,
decreased body size,
decreased coping response,
decreased dopamine level,
decreased dopaminergic neuron number,
decreased locomotor activity,
decreased physiological sensitivity to xenobiotic,
decreased serotonin level,
decreased vertical activity,
enhanced behavioral response to addictive substance,
enhanced long term potentiation,
impaired behavioral response to cocaine,
impaired conditioned place preference behavior,
impaired olfaction,
increased anxiety-related response,
increased defecation amount,
increased susceptibility to dopaminergic neuron neurotoxicity,
muscle phenotype,
neonatal lethality, complete penetrance,
neonatal lethality, incomplete penetrance,
nervous system phenotype,
neuron degeneration,
postnatal lethality, complete penetrance,
postnatal lethality, incomplete penetrance,
premature death,
vision/eye phenotype
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View all ortholog results at Monarch
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