|
XB-GENEPAGE-855724
kmt2d lysine methyltransferase 2D
Anatomical Phenotypes
![]() |
---|
abnormal development of heart (5 sources), abnormal heart morphology (4 sources), abnormal development of heart primordium (2 sources), abnormal neural crest morphology (2 sources), abnormal cartilage tissue morphology (1 source), abnormal cell migration in neural crest (1 source), abnormal craniofacial region morphology (1 source), abnormal craniofacial skeleton (1 source), abnormal development of primary heart field (1 source), abnormal development of secondary heart field (1 source), abnormal eye morphology (1 source), abnormal histone methylation (1 source), decreased size of the cranial skeleton (1 source) |
Expression Phenotypes
![]() |
---|
Manual annotations: kmt2d manipulated (19 sources) |
Diseases
![]() |
---|
Kabuki syndrome (12AP sources, 6 EP sources), congenital heart disease (9AP sources, 5 EP sources) |
Experiments (Reagents)
![]() |
---|
Xla Wt + kmt2d MO (10 sources), Xla Wt + kmt2d MO (6 sources), Xla Wt + kmt2d MO (6 sources), Xla Wt + kmt2d MO (3 sources), Xla Wt + kmt2d MO (1 source), Xla Wt + kmt2d MO (1 source) |
Monarch Ortholog Phenotypes
![]() |
---|
Human (96 sources): Abnormal cardiac septum morphology, Abnormal dermatoglyphics, Abnormal form of the vertebral bodies, Abnormal localization of kidney, Abnormal vertebral morphology, Abnormality of dental morphology, Abnormality of immune system physiology, Abnormality of the dentition, Anal atresia, Anal stenosis, [+] |
Mouse (40 sources): abnormal brown fat cell differentiation, abnormal dentate gyrus morphology, abnormal fetal cardiomyocyte morphology, abnormal heart echocardiography feature, abnormal heart tube morphology, abnormal hippocampus granule cell layer, abnormal inner ear canal morphology, abnormal motor capabilities/coordination/movement, abnormal object recognition memory, abnormal pinna reflex, [+] |
View all ortholog results at Monarch |