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XB-GENEPAGE-6465483
ets1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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decreased pigmentation in the whole organism (5 sources), decreased size of the head (5 sources), abnormally decreased mobility of migratory neural crest cell (2 sources), abnormally incomplete structure of head (2 sources), abnormally irregular spatial pattern of cranial neural crest (2 sources), abnormally ruffled dorsal fin (2 sources), increased apoptosis in neural plate border (2 sources) |
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Manual annotations: ets1 manipulated (32 sources), ets1 assayed (3 sources) |
Computed annotations: ets1 assayed (4 sources) |
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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Xla Wt + ets1 (9 sources), Xla Wt + ets1 (5 sources), Xla Wt + ets1 MO (4 sources), Xla Wt + ets1del_1-450 (4 sources), Xla Wt + ets1del_1-906 (4 sources), Xla Wt + ets1 (3 sources), Xla Wt + ets1 MO (3 sources), Xla Wt + ets1-GR + DEX (3 sources), Xla Wt + ets1 + TSA (2 sources), Xla Wt + ets1 MO (2 sources), Xla Wt + ets1del_1044-1314 (2 sources), Xla Wt + ets1del_783-1314 (2 sources), Xla Wt + ets1-GR + DEX (1 source), Xla Wt + dnets1-GR + DEX (1 source) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Human (1 source): Hepatic fibrosis |
Mouse (38 sources): abnormal CD8-positive, alpha beta T cell morphology, abnormal CD8-positive, alpha-beta T cell differentiation, abnormal T cell activation, abnormal leukocyte physiology, abnormal lymphopoiesis, abnormal spleen red pulp morphology, abnormal thymus cortex morphology, abnormal thymus morphology, abnormal thymus subcapsular epithelium morphology, absent B-1a cells, [+] |
View all ortholog results at Monarch |