| Monarch Ortholog Phenotypes
|
Human (27 sources):
Atrophic scars,
Bilateral ptosis,
Bruising susceptibility,
Bursitis,
Cellulitis,
Cryptorchidism,
Hallux valgus,
High palate,
Hip dislocation,
Hyperextensible skin,
Knee dislocation,
Low posterior hairline,
Macrotia,
Micrognathia,
Mitral valve prolapse,
Osteoarthritis,
Osteoporosis,
Pes planus,
Redundant skin,
Short neck,
Shoulder dislocation,
Squared iliac bones,
Thin eyebrow,
Thoracic scoliosis,
Umbilical hernia,
Ventral hernia,
Webbed neck
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Mouse (23 sources):
abnormal embryo size,
abnormal fat cell morphology,
abnormal involution of the mammary gland,
abnormal nursing,
abnormal tail morphology,
abnormal white adipose tissue morphology,
curly tail,
decreased cell proliferation,
decreased survivor rate,
decreased susceptibility to diet-induced obesity,
decreased white adipose tissue amount,
impaired wound healing,
increased food intake,
increased sensitivity to induced morbidity/mortality,
increased susceptibility to weight gain,
increased white adipose tissue amount,
kinked tail,
perinatal lethality, incomplete penetrance,
premature death,
prenatal lethality, incomplete penetrance,
preweaning lethality, complete penetrance,
shortened RR interval,
skin lesions
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.