| Monarch Ortholog Phenotypes
|
Human (41 sources):
Abnormality of the coagulation cascade,
Achromatopsia,
Acute hepatic failure,
Brachycephaly,
Brachydactyly,
Cardiomyopathy,
Cutis laxa,
Delayed skeletal maturation,
Elevated circulating hepatic transaminase concentration,
Epicanthus,
Facial asymmetry,
Failure to thrive,
Fine hair,
Hepatic encephalopathy,
Hyperammonemia,
Hypermetropia,
Hypertelorism,
Hypoglycemia,
Hypotonia,
Jaundice,
Lethargy,
Long face,
Long philtrum,
Micromelia,
Myopia,
Narrow forehead,
Nonprogressive visual loss,
Optic atrophy,
Prominent glabella,
Proptosis,
Reduced visual acuity,
Sandal gap,
Seizure,
Short neck,
Short stature,
Single transverse palmar crease,
Strabismus,
Syndactyly,
Thick eyebrow,
Thin vermilion border,
Vomiting
[+]
|
|
Mouse (6 sources):
abnormal retina blood vessel morphology,
abnormal retina vasculature morphology,
increased circulating alkaline phosphatase level,
increased fasting circulating glucose level,
persistence of hyaloid vascular system,
preweaning lethality, complete penetrance
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.