Monarch Ortholog Phenotypes
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Human (53 sources):
Anteriorly placed anus,
Arrhythmia,
Atrial septal defect,
Atrioventricular block,
Decreased plasma carnitine,
Dicarboxylic aciduria,
Dilated cardiomyopathy,
Elevated circulating creatine kinase concentration,
Elevated circulating hepatic transaminase concentration,
Enlarged cisterna magna,
Episodic tachypnea,
Exercise-induced myalgia,
Exercise-induced myoglobinuria,
Exercise-induced rhabdomyolysis,
Feeding difficulties,
Generalized hypotonia,
Hepatic steatosis,
Hepatocellular necrosis,
Hepatomegaly,
Hyperammonemia,
Hypertrophic cardiomyopathy,
Hypocalcemia,
Hypoketotic hypoglycemia,
Hypoproteinemia,
Hypothermia,
Hypotonia,
Increased circulating free fatty acid level,
Infantile muscular hypotonia,
Inflammatory abnormality of the skin,
Jaundice,
Lethargy,
Macrocephaly,
Metabolic acidosis,
Muscle spasm,
Muscle stiffness,
Muscle weakness,
Nonketotic hypoglycemia,
Obesity,
Overweight,
Pain,
Patent foramen ovale,
Pericardial effusion,
Pneumonia,
Prolonged QT interval,
Respiratory distress,
Small for gestational age,
Sudden cardiac death,
Tachycardia,
Tachypnea,
Ventricular fibrillation,
Ventricular septal defect,
Ventricular tachycardia,
Vomiting
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Mouse (21 sources):
abnormal adaptive thermogenesis,
abnormal adipose tissue physiology,
abnormal amino acid level,
abnormal brown adipose tissue morphology,
abnormal cellular respiration,
abnormal lipid homeostasis,
abnormal myocardial fiber morphology,
decreased circulating glucose level,
decreased core body temperature,
decreased glycogen level,
decreased respiratory quotient,
decreased ventricle muscle contractility,
dilated heart left ventricle,
impaired adaptive thermogenesis,
increased circulating carnitine level,
increased heart weight,
increased sensitivity to induced morbidity/mortality,
increased tumor incidence,
macrovesicular hepatic steatosis,
myocardial fiber degeneration,
premature death
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View all ortholog results at Monarch
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