c1h9orf72 Phenotypes

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Phenotypes

Gene Literature (4)

Nucleotides (123)

Interactants (32)

XB-GENEPAGE-5871696

Gene Symbol: c1h9orf72 Gene Name: chromosome 1 C9orf72 homolog

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (77 sources): Abnormal lower motor neuron morphology, Abnormal mitochondrial morphology, Abnormal respiratory system physiology, Abnormal upper motor neuron morphology, Abnormality of extrapyramidal motor function, Agitation, Amyotrophic lateral sclerosis, Anxiety, Apathy, Apraxia, Ataxia, Atypical behavior, Babinski sign, Bilateral sensorineural hearing impairment, Bulbar palsy, Cerebral atrophy, Chorea, Cognitive impairment, Degeneration of anterior horn cells, Degeneration of the lateral corticospinal tracts, Delusion, Dementia, Depression, Disinhibition, Distal muscle weakness, Dysarthria, Dyscalculia, Dysphagia, Dyspnea, Dystonia, Emotional lability, Extrapyramidal dyskinesia, Fasciculations, Fatigable weakness of bulbar muscles, Fatigable weakness of respiratory muscles, Fatigable weakness of swallowing muscles, Fatigue, Frontotemporal dementia, Generalized amyotrophy, Generalized muscle weakness, Gliosis, Global brain atrophy, Hallucinations, Hyperreflexia, Hyporeflexia, Inappropriate behavior, Laryngospasm, Memory impairment, Muscle spasm, Muscle weakness, Mutism, Myoclonus, Nausea and vomiting, Neurodegeneration, Neuronal loss in central nervous system, Neuronal loss in the cerebral cortex, Pain, Paralysis, Paraparesis, Parkinsonism, Perseverative thought, Progressive cerebellar ataxia, Proximal muscle weakness, Pseudobulbar paralysis, Psychosis, Ptosis, Respiratory insufficiency, Rigidity, Skeletal muscle atrophy, Sleep apnea, Spasticity, Supranuclear gaze palsy, Tetraparesis, Tremor, Upper motor neuron dysfunction, Weakness due to upper motor neuron dysfunction, Xerostomia [+]
Mouse (34 sources): abnormal adipose tissue amount, abnormal celiac lymph node morphology, abnormal cervical lymph node morphology, abnormal circulating alkaline phosphatase level, abnormal circulating cytokine level, abnormal circulating interleukin level, abnormal lean body mass, abnormal lymph node cell ratio, abnormal macrophage physiology, abnormal microglial cell physiology, abnormal social investigation, abnormal spinal cord grey matter morphology, abnormal spinal cord white matter morphology, behavior/neurological phenotype, decreased circulating interleukin-2 level, decreased erythrocyte cell number, decreased hematocrit, decreased hemoglobin content, decreased mean corpuscular volume, decreased startle reflex, dermatitis, enlarged cervical lymph nodes, enlarged lymph nodes, increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number, increased anti-double stranded DNA antibody level, increased autoantibody level, increased circulating alkaline phosphatase level, increased lean body mass, increased neutrophil cell number, increased splenocyte number, increased susceptibility to autoimmune disorder, lysosomal protein accumulation, nervous system phenotype, premature death [+]
View all ortholog results at Monarch