Human (66 sources):
Abnormal mitochondria in muscle tissue,
Acute necrotizing encephalopathy,
Ataxia,
Babinski sign,
Blindness,
Cerebellar atrophy,
Cerebral edema,
Coma,
Decreased activity of mitochondrial complex I,
Decreased activity of mitochondrial respiratory chain,
Developmental regression,
Diabetes mellitus,
Dyskinesia,
Dystonia,
Encephalopathy,
Exercise intolerance,
Failure to thrive,
Feeding difficulties,
Feeding difficulties in infancy,
Fetal distress,
Flexion contracture,
Focal T2 hyperintense brainstem lesion,
Generalized hypotonia,
Global developmental delay,
Growth delay,
Hearing impairment,
Hepatic failure,
Hepatomegaly,
Hyperreflexia,
Hypertrophic cardiomyopathy,
Hypoglycemia,
Hyporeflexia,
Hypotonia,
Increased CSF lactate,
Increased serum pyruvate,
Intrauterine growth retardation,
Irritability,
Kyphosis,
Lactic acidosis,
Lethargy,
Leukodystrophy,
Leukoencephalopathy,
Metabolic acidosis,
Microcephaly,
Mitochondrial myopathy,
Muscle weakness,
Myopathy,
Nystagmus,
Optic atrophy,
Optic disc pallor,
Optic neuropathy,
Paroxysmal involuntary eye movements,
Peripheral demyelination,
Poor head control,
Progressive macrocephaly,
Proximal tubulopathy,
Ptosis,
Reduced eye contact,
Respiratory insufficiency,
Seizure,
Sensorineural hearing impairment,
Skeletal muscle atrophy,
Spastic tetraplegia,
Spasticity,
Strabismus,
Vomiting
[+]
|