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Summary Expression Phenotypes Gene Literature (3) GO Terms (4) Nucleotides (202) Proteins (63) Interactants (320) Wiki
XB-GENEPAGE-492495

sesn2     sestrin 2

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: sesn2 assayed (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (10 sources): abnormal autophagy, abnormal gluconeogenesis, decreased adipocyte glucose uptake, decreased lung fibroblast proliferation, decreased mitochondrial DNA content, growth/size/body region phenotype, increased cellular sensitivity to hydrogen peroxide, increased fibroblast apoptosis, increased liver triglyceride level, macrovesicular hepatic steatosis