rbm38 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-489544

Gene Symbol: rbm38 Gene Name: RNA binding motif protein 38

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal head morphology (3 sources), abnormal anterior-posterior axis, curved dorsal (2 sources), increased pigmentation in the trunk (2 sources), abnormal alimentary system morphology (1 source), abnormal bending of anterior-posterior axis (1 source), abnormal cell migration in neural crest (1 source), abnormal development of eye (1 source), abnormal development of fin (1 source), abnormally ruffled ventral fin margin (1 source), abnormal neural crest morphology (1 source), absent eye (1 source), decreased pigmentation in the eye (1 source), decreased pigmentation in the whole organism (1 source), decreased size of the eye (1 source), increased apoptosis in embryo (1 source), increased apoptosis in head (1 source), increased apoptosis in trunk (1 source), increased size of the ventral trunk (1 source), obsolete abnormal histone phosphorylation (1 source)

Anatomical Phenotypes

Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.

abnormal head morphology (3 sources), abnormal anterior-posterior axis, curved dorsal (2 sources), increased pigmentation in the trunk (2 sources), abnormal alimentary system morphology (1 source), abnormal bending of anterior-posterior axis (1 source), abnormal cell migration in neural crest (1 source), abnormal development of eye (1 source), abnormal development of fin (1 source), abnormally ruffled ventral fin margin (1 source), abnormal neural crest morphology (1 source), absent eye (1 source), decreased pigmentation in the eye (1 source), decreased pigmentation in the whole organism (1 source), decreased size of the eye (1 source), increased apoptosis in embryo (1 source), increased apoptosis in head (1 source), increased apoptosis in trunk (1 source), increased size of the ventral trunk (1 source), obsolete abnormal histone phosphorylation (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: rbm38 manipulated (16 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + rbm38 (14 sources), Xla Wt + rbm38 MO (3 sources), Xla Wt + rbm38 (1 source), Xla Wt + rbm38 (1 source), Xla Wt + rbm38 (1 source), Xla Wt + rbm38del (1 source), Xla Wt + rbm38-GR + DEX (1 source), Xla Wt + rbm38-GR + DEX (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (11 sources): decreased bone marrow cell number, decreased gonadal fat pad weight, decreased hematocrit, decreased hemoglobin content, increased hepatoma incidence, increased lymphoma incidence, increased mortality induced by gamma-irradiation, increased spleen white pulp amount, increased tumor incidence, premature aging, premature death [+]