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XB-GENEPAGE-486051
lrp2 LDL receptor related protein 2
Anatomical Phenotypes
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abnormal apical constriction (7 sources), abnormal incomplete closing of the neural fold (7 sources), abnormal neural fold morphology (6 sources), abnormal cell morphology (3 sources), increased size of the floor plate (2 sources), abnormal development of optic vesicle (1 source), abnormal establishment of planar polarity (1 source), abnormal forebrain morphology (1 source), abnormal neural plate morphology (1 source), abnormal neural tube morphology (1 source) |
Expression Phenotypes
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Manual annotations: lrp2 manipulated (2 sources), lrp2 assayed (1 source) |
Computed annotations: lrp2 assayed (3 sources) |
Experiments (Reagents)
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Xla Wt + lrp2 MO (6 sources), Xla Wt + lrp2 MO (3 sources), Xla Wt + lrp2 CRISPR (2 sources), Xla Wt + lrp2 MO (2 sources), Xla Wt + gipc1 MO + lrp2 MO (1 source), Xla Wt + lrp2 CRISPR (1 source) |
Monarch Ortholog Phenotypes
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Human (40 sources): Abnormality of the uterus, Aplasia/Hypoplasia of the corpus callosum, Bicornuate uterus, Broad forehead, Broad nasal tip, Cataract, Congenital diaphragmatic hernia, Depressed nasal bridge, Diaphragmatic eventration, Downslanted palpebral fissures, [+] |
Mouse (60 sources): abnormal bone mineralization, abnormal bone remodeling, abnormal cerebellum fissure morphology, abnormal cerebral cortex morphology, abnormal choroid plexus morphology, abnormal circulating mineral level, abnormal dendrite morphology, abnormal diencephalon morphology, abnormal embryonic neuroepithelium morphology, abnormal forebrain development, [+] |
View all ortholog results at Monarch |