| Monarch Ortholog Phenotypes
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Human (29 sources):
Abnormal hair morphology,
Abnormal hair pattern,
Abnormal respiratory system morphology,
Abnormality of the 5th toe,
Abnormality of the kidney,
Anal stenosis,
Anophthalmia,
Anteriorly placed anus,
Bifid nasal tip,
Bifid nose,
Bulbous nose,
Cryptophthalmos,
Eyelid coloboma,
Hypertelorism,
Hypotelorism,
Metopic synostosis,
Microcephaly,
Microphthalmia,
Nasolacrimal duct obstruction,
Omphalocele,
Prominent supraorbital ridges,
Rectovaginal fistula,
Renal agenesis,
Short lingual frenulum,
Short philtrum,
Synophrys,
Trigonocephaly,
Upper eyelid coloboma,
Wide nasal bridge
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Mouse (24 sources):
abnormal anogenital distance,
abnormal craniofacial morphology,
abnormal diaphragm development,
abnormal eye development,
abnormal internasal suture morphology,
abnormal kidney development,
abnormal kidney morphology,
abnormal maxillary-premaxillary suture morphology,
abnormal metopic suture morphology,
abnormal midface morphology,
abnormal nasal bone morphology,
abnormal postnatal growth/weight/body size,
absent corneal epithelium,
asymmetric snout,
bleb,
broad nasal bone,
early eyelid opening,
eyelids fail to open,
eyelids open at birth,
fused right lung lobes,
no abnormal phenotype detected,
premature metopic suture closure,
prenatal lethality, incomplete penetrance,
preweaning lethality, incomplete penetrance
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.