Monarch Ortholog Phenotypes
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Human (12 sources):
Abnormal intestine morphology,
Anisocytosis,
Decreased circulating copper concentration,
Elevated circulating hepcidin concentration,
Hyperkeratosis,
Hypochromic microcytic anemia,
Ichthyosis,
Intellectual disability,
Intrahepatic cholestasis,
Pallor,
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Mouse (47 sources):
abnormal circulating calcium level,
abnormal coat appearance,
abnormal exploration in a new environment,
abnormal grip strength,
abnormal hair follicle infundibulum morphology,
abnormal hair follicle morphology,
abnormal intestinal mineral absorption,
abnormal iron level,
abnormal locomotor activation,
abnormal ovary development,
abnormal prepulse inhibition,
abnormal startle reflex,
decreased body size,
decreased circulating iron level,
decreased erythrocyte cell number,
decreased exploration in new environment,
decreased grip strength,
decreased heart iron level,
decreased hematocrit,
decreased hemoglobin content,
decreased liver iron level,
decreased locomotor activity,
decreased mean corpuscular hemoglobin,
decreased mean corpuscular hemoglobin concentration,
decreased mean corpuscular volume,
decreased pancreas iron level,
decreased prepulse inhibition,
decreased spleen iron level,
focal hair loss,
hematopoietic system phenotype,
immune system phenotype,
increased Ly6C-positive mature NK cell number,
increased anxiety-related response,
increased circulating unsaturated transferrin level,
increased effector memory CD8-positive, alpha-beta T cell number,
increased fasting circulating glucose level,
increased memory-marker CD4-negative NK T cell number,
increased red blood cell distribution width,
increased spleen weight,
increased startle reflex,
increased thigmotaxis,
maternal effect,
microcytosis,
postnatal lethality, incomplete penetrance,
progressive hair loss,
reduced female fertility,
thin hair follicle outer root sheath
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View all ortholog results at Monarch
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