Monarch Ortholog Phenotypes
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Human (19 sources):
Abnormal cerebral morphology,
Cerebral hemorrhage,
Choroidal hemangioma,
Cognitive impairment,
Episodic vomiting,
Focal T2 hyperintense brainstem lesion,
Focal T2 hypointense brainstem lesion,
Headache,
Hemangioma,
Increased intracranial pressure,
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Mouse (42 sources):
CNS inflammation,
abnormal angiogenesis,
abnormal astrocyte morphology,
abnormal brain vasculature morphology,
abnormal cardiac jelly morphology,
abnormal cardinal vein morphology,
abnormal developmental vascular remodeling,
abnormal dorsal aorta morphology,
abnormal endocardium morphology,
abnormal intersomitic vessel morphology,
abnormal myocardium layer morphology,
abnormal pericyte morphology,
abnormal retina vasculature morphology,
abnormal vascular branching morphogenesis,
abnormal vascular endothelial cell migration,
abnormal vasculogenesis,
abnormal vitelline vascular remodeling,
abnormal vitelline vasculature morphology,
cardiovascular system phenotype,
circling,
decreased embryo size,
dilated dorsal aorta,
dilated vasculature,
embryonic growth arrest,
embryonic lethality between somite formation and embryo turning, complete penetrance,
embryonic lethality between somite formation and embryo turning, incomplete penetrance,
embryonic lethality during organogenesis, complete penetrance,
enlarged pericardium,
impaired hematopoiesis,
increased brain size,
increased circulating creatinine level,
increased hemangioma incidence,
lethality throughout fetal growth and development, complete penetrance,
myocardial trabeculae hypoplasia,
nervous system phenotype,
no abnormal phenotype detected,
postnatal lethality,
postnatal lethality, complete penetrance,
postnatal lethality, incomplete penetrance,
premature death,
prenatal lethality, incomplete penetrance,
thin myocardium
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View all ortholog results at Monarch
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