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Summary Expression Phenotypes Gene Literature (108) GO Terms (12) Nucleotides (62) Proteins (34) Interactants (83) Wiki

Papers associated with kcnb1

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Mono-allelic KCNB2 variants lead to a neurodevelopmental syndrome caused by altered channel inactivation., Bhat S, Rousseau J, Michaud C, Lourenço CM, Stoler JM, Louie RJ, Clarkson LK, Lichty A, Koboldt DC, Reshmi SC, Sisodiya SM, Hoytema van Konijnenburg EMM, Koop K, van Hasselt PM, Démurger F, Dubourg C, Sullivan BR, Hughes SS, Thiffault I, Tremblay ES, Accogli A, Srour M, Blunck R, Campeau PM., Am J Hum Genet. April 4, 2024; 111 (4): 761-777.

Extracellular Linkers Completely Transplant the Voltage Dependence from Kv1.2 Ion Channels to Kv2.1., Elinder F, Madeja M, Zeberg H, Århem P., Biophys J. October 18, 2016; 111 (8): 1679-1691.

Expression and function of a CP339,818-sensitive K⁺ current in a subpopulation of putative nociceptive neurons from adult mouse trigeminal ganglia., Sforna L, D'Adamo MC, Servettini I, Guglielmi L, Pessia M, Franciolini F, Catacuzzeno L., J Neurophysiol. April 1, 2015; 113 (7): 2653-65.

A surface plasmon resonance approach to monitor toxin interactions with an isolated voltage-gated sodium channel paddle motif., Martin-Eauclaire MF, Ferracci G, Bosmans F, Bougis PE., J Gen Physiol. February 1, 2015; 145 (2): 155-62.        

Tarantula toxins use common surfaces for interacting with Kv and ASIC ion channels., Gupta K, Zamanian M, Bae C, Milescu M, Krepkiy D, Tilley DC, Sack JT, Yarov-Yarovoy V, Kim JI, Swartz KJ., Elife. January 6, 2015; 4 e06774.                

Analysis of the interaction of tarantula toxin Jingzhaotoxin-III (β-TRTX-Cj1α) with the voltage sensor of Kv2.1 uncovers the molecular basis for cross-activities on Kv2.1 and Nav1.5 channels., Tao H, Chen JJ, Xiao YC, Wu YY, Su HB, Li D, Wang HY, Deng MC, Wang MC, Liu ZH, Liang SP., Biochemistry. October 22, 2013; 52 (42): 7439-48.

Molecular determinants for the tarantula toxin jingzhaotoxin-I interacting with potassium channel Kv2.1., Tao H, Wu Y, Deng M, He J, Wang M, Xiao Y, Liang S., Toxicon. March 1, 2013; 63 129-36.

Opening the shaker K+ channel with hanatoxin., Milescu M, Lee HC, Bae CH, Kim JI, Swartz KJ., J Gen Physiol. February 1, 2013; 141 (2): 203-16.              

Homology model and targeted mutagenesis identify critical residues for arachidonic acid inhibition of Kv4 channels., Heler R, Bell JK, Boland LM., Channels (Austin). January 1, 2013; 7 (2): 74-84.              

A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel., Pless SA, Niciforovic AP, Galpin JD, Nunez JJ, Kurata HT, Ahern CA., Nat Commun. January 1, 2013; 4 1784.              

Functional analysis of missense mutations in Kv8.2 causing cone dystrophy with supernormal rod electroretinogram., Smith KE, Wilkie SE, Tebbs-Warner JT, Jarvis BJ, Gallasch L, Stocker M, Hunt DM., J Biol Chem. December 21, 2012; 287 (52): 43972-83.

Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1., Aidery P, Kisselbach J, Schweizer PA, Becker R, Katus HA, Thomas D., Gene. December 10, 2012; 511 (1): 26-33.        

Intermediate state trapping of a voltage sensor., Lacroix JJ, Pless SA, Maragliano L, Campos FV, Galpin JD, Ahern CA, Roux B, Bezanilla F., J Gen Physiol. December 1, 2012; 140 (6): 635-52.                      

JZTX-XIII, a Kv channel gating modifier toxin from Chinese tarantula Chilobrachys jingzhao., Yuan C, Liu Z, Hu W, Gao T, Liang S., Toxicon. February 1, 2012; 59 (2): 265-71.

R1 in the Shaker S4 occupies the gating charge transfer center in the resting state., Lin MC, Hsieh JY, Mock AF, Papazian DM., J Gen Physiol. August 1, 2011; 138 (2): 155-63.                  

Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensors., Bosmans F, Puopolo M, Martin-Eauclaire MF, Bean BP, Swartz KJ., J Gen Physiol. July 1, 2011; 138 (1): 59-72.                  

Overlapping binding sites of structurally different antiarrhythmics flecainide and propafenone in the subunit interface of potassium channel Kv2.1., Madeja M, Steffen W, Mesic I, Garic B, Zhorov BS., J Biol Chem. October 29, 2010; 285 (44): 33898-905.

Solution structure of GxTX-1E, a high-affinity tarantula toxin interacting with voltage sensors in Kv2.1 potassium channels ., Lee S, Milescu M, Jung HH, Lee JY, Bae CH, Lee CW, Kim HH, Swartz KJ, Kim JI., Biochemistry. June 29, 2010; 49 (25): 5134-42.

Transfer of ion binding site from ether-a-go-go to Shaker: Mg2+ binds to resting state to modulate channel opening., Lin MC, Abramson J, Papazian DM., J Gen Physiol. May 1, 2010; 135 (5): 415-31.                    

Rearrangements in the relative orientation of cytoplasmic domains induced by a membrane-anchored protein mediate modulations in Kv channel gating., Lvov A, Greitzer D, Berlin S, Chikvashvili D, Tsuk S, Lotan I, Michaelevski I., J Biol Chem. October 9, 2009; 284 (41): 28276-91.

Mutations reveal voltage gating of CNGA1 channels in saturating cGMP., Martínez-François JR, Xu Y, Xu Y, Lu Z., J Gen Physiol. August 1, 2009; 134 (2): 151-64.                      

Jingzhaotoxin-IX, a novel gating modifier of both sodium and potassium channels from Chinese tarantula Chilobrachys jingzhao., Deng M, Kuang F, Sun Z, Tao H, Cai T, Zhong L, Chen Z, Xiao Y, Liang S., Neuropharmacology. August 1, 2009; 57 (2): 77-87.

The analysis of desensitizing CNGA1 channels reveals molecular interactions essential for normal gating., Mazzolini M, Anselmi C, Torre V., J Gen Physiol. April 1, 2009; 133 (4): 375-86.            

Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels., Lee SY, Banerjee A, MacKinnon R., PLoS Biol. March 3, 2009; 7 (3): e47.              

Dynamic coupling of voltage sensor and gate involved in closed-state inactivation of kv4.2 channels., Barghaan J, Bähring R., J Gen Physiol. February 1, 2009; 133 (2): 205-24.                    

Contribution of the central hydrophobic residue in the PXP motif of voltage-dependent K+ channels to S6 flexibility and gating properties., Imbrici P, Grottesi A, D'Adamo MC, Mannucci R, Tucker SJ, Pessia M., Channels (Austin). January 1, 2009; 3 (1): 39-45.

Deconstructing voltage sensor function and pharmacology in sodium channels., Bosmans F, Martin-Eauclaire MF, Swartz KJ., Nature. November 13, 2008; 456 (7219): 202-8.          

Localization of Kv2.2 protein in Xenopus laevis embryos and tadpoles., Gravagna NG, Knoeckel CS, Taylor AD, Hultgren BA, Ribera AB., J Comp Neurol. October 10, 2008; 510 (5): 508-24.                        

VAMP2 interacts directly with the N terminus of Kv2.1 to enhance channel inactivation., Lvov A, Chikvashvili D, Michaelevski I, Lotan I., Pflugers Arch. September 1, 2008; 456 (6): 1121-36.

Formation of the full SNARE complex eliminates interactions of its individual protein components with the Kv2.1 channel., Tsuk S, Lvov A, Michaelevski I, Chikvashvili D, Lotan I., Biochemistry. August 12, 2008; 47 (32): 8342-9.

Atomic constraints between the voltage sensor and the pore domain in a voltage-gated K+ channel of known structure., Lewis A, Jogini V, Blachowicz L, Lainé M, Roux B., J Gen Physiol. June 1, 2008; 131 (6): 549-61.                

An extracellular Cu2+ binding site in the voltage sensor of BK and Shaker potassium channels., Ma Z, Wong KY, Horrigan FT., J Gen Physiol. May 1, 2008; 131 (5): 483-502.                      

Tarantula toxins interact with voltage sensors within lipid membranes., Milescu M, Vobecky J, Roh SH, Kim SH, Jung HJ, Kim JI, Swartz KJ., J Gen Physiol. November 1, 2007; 130 (5): 497-511.                    

Characterization of the heteromeric potassium channel formed by kv2.1 and the retinal subunit kv8.2 in Xenopus oocytes., Czirjak G, Toth ZE, Enyedi P., J Neurophysiol. September 1, 2007; 98 (3): 1213-22.

Solution structure of Jingzhaotoxin-III, a peptide toxin inhibiting both Nav1.5 and Kv2.1 channels., Liao Z, Yuan C, Peng K, Xiao Y, Liang S., Toxicon. July 1, 2007; 50 (1): 135-43.

Effects and mechanism of Chinese tarantula toxins on the Kv2.1 potassium channels., Yuan C, Yang S, Liao Z, Liang S., Biochem Biophys Res Commun. January 19, 2007; 352 (3): 799-804.

Target soluble N-ethylmaleimide-sensitive factor attachment protein receptors (t-SNAREs) differently regulate activation and inactivation gating of Kv2.2 and Kv2.1: Implications on pancreatic islet cell Kv channels., Wolf-Goldberg T, Michaelevski I, Sheu L, Gaisano HY, Chikvashvili D, Lotan I., Mol Pharmacol. September 1, 2006; 70 (3): 818-28.

1,4-Diazabicyclo[2.2.2]octane derivatives: a novel class of voltage-gated potassium channel blockers., Gordon E, Cohen JL, Engel R, Abbott GW., Mol Pharmacol. March 1, 2006; 69 (3): 718-26.

Allosteric effects of external K+ ions mediated by the aspartate of the GYGD signature sequence in the Kv2.1 K+ channel., Chapman ML, Blanke ML, Krovetz HS, VanDongen AM., Pflugers Arch. March 1, 2006; 451 (6): 776-92.

Endogenous KCNE subunits govern Kv2.1 K+ channel activation kinetics in Xenopus oocyte studies., Gordon E, Roepke TK, Abbott GW., Biophys J. February 15, 2006; 90 (4): 1223-31.

Analysis of voltage-gated potassium channel beta1 subunits in the porcine neonatal ductus arteriosus., Hayama E, Imamura S, Wu C, Nakazawa M, Matsuoka R, Nakanishi T., Pediatr Res. February 1, 2006; 59 (2): 167-74.

Pharmacology and surface electrostatics of the K channel outer pore vestibule., Quinn CC, Begenisich T., J Membr Biol. January 1, 2006; 212 (1): 51-60.              

K channel subconductance levels result from heteromeric pore conformations., Chapman ML, VanDongen AM., J Gen Physiol. August 1, 2005; 126 (2): 87-103.                                

Kv2.1 channel activation and inactivation is influenced by physical interactions of both syntaxin 1A and the syntaxin 1A/soluble N-ethylmaleimide-sensitive factor-25 (t-SNARE) complex with the C terminus of the channel., Tsuk S, Michaelevski I, Bentley GN, Joho RH, Chikvashvili D, Lotan I., Mol Pharmacol. February 1, 2005; 67 (2): 480-8.

Effects of intracellular magnesium on Kv1.5 and Kv2.1 potassium channels., Tammaro P, Smirnov SV, Moran O., Eur Biophys J. February 1, 2005; 34 (1): 42-51.

Stabilizing the closed S6 gate in the Shaker Kv channel through modification of a hydrophobic seal., Kitaguchi T, Sukhareva M, Swartz KJ., J Gen Physiol. October 1, 2004; 124 (4): 319-32.                              

Effects of Kv1.2 intracellular regions on activation of Kv2.1 channels., Scholle A, Zimmer T, Koopmann R, Engeland B, Pongs O, Benndorf K., Biophys J. August 1, 2004; 87 (2): 873-82.

Modification of Kv2.1 K+ currents by the silent Kv10 subunits., Vega-Saenz de Miera EC., Brain Res Mol Brain Res. April 7, 2004; 123 (1-2): 91-103.

Molecular surface of tarantula toxins interacting with voltage sensors in K(v) channels., Wang JM, Roh SH, Kim S, Lee CW, Kim JI, Swartz KJ., J Gen Physiol. April 1, 2004; 123 (4): 455-67.                

Solution structure and functional characterization of SGTx1, a modifier of Kv2.1 channel gating., Lee CW, Kim S, Roh SH, Endoh H, Kodera Y, Maeda T, Kohno T, Wang JM, Swartz KJ, Kim JI., Biochemistry. February 3, 2004; 43 (4): 890-7.

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