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Summary Expression Phenotypes Gene Literature (80) GO Terms (4) Nucleotides (52) Proteins (29) Interactants (159) Wiki

Papers associated with kcna5

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Electrophysiological effects of non-vitamin K antagonist oral anticoagulants on atrial repolarizing potassium channels., Wiedmann F, Schlund D, Kraft M, Nietfeld J, Katus HA, Schmidt C, Thomas D., Europace. September 1, 2020; 22 (9): 1409-1418.

Insights into electrosensory organ development, physiology and evolution from a lateral line-enriched transcriptome., Modrell MS, Lyne M, Carr AR, Zakon HH, Buckley D, Campbell AS, Davis MC, Micklem G, Baker CV., Elife. March 27, 2017; 6             

SGK3 Sensitivity of Voltage Gated K+ Channel Kv1.5 (KCNA5)., Ahmed M, Fezai M, Uzcategui NL, Hosseinzadeh Z, Lang F., Cell Physiol Biochem. January 1, 2016; 38 (1): 359-67.

Regulation of Voltage-Gated K+ Channel Kv1.5 by the Janus Kinase JAK3., Warsi J, Elvira B, Bissinger R, Hosseinzadeh Z, Lang F., J Membr Biol. December 1, 2015; 248 (6): 1061-70.

Kv1.5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea?, Kiper AK, Rinné S, Rolfes C, Ramírez D, Seebohm G, Netter MF, González W, Decher N., Pflugers Arch. May 1, 2015; 467 (5): 1081-90.

Endogenous gradients of resting potential instructively pattern embryonic neural tissue via Notch signaling and regulation of proliferation., Pai VP, Lemire JM, Paré JF, Lin G, Chen Y, Levin M., J Neurosci. March 11, 2015; 35 (10): 4366-85.                    

SPAK and OSR1 sensitivity of voltage-gated K+ channel Kv1.5., Elvira B, Warsi J, Munoz C, Lang F., J Membr Biol. February 1, 2015; 248 (1): 59-66.

Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos., Chernet BT, Fields C, Levin M., Front Physiol. January 19, 2015; 5 519.                

Inhibitory effects of cortisone and hydrocortisone on human Kv1.5 channel currents., Yu J, Park MH, Jo SH., Eur J Pharmacol. January 5, 2015; 746 158-66.

PKC and AMPK regulation of Kv1.5 potassium channels., Andersen MN, Skibsbye L, Tang C, Petersen F, MacAulay N, Rasmussen HB, Jespersen T., Channels (Austin). January 1, 2015; 9 (3): 121-8.

Up-Regulation of Voltage Gated K+ Channels Kv1.3 and Kv1.5 by Protein Kinase PKB/Akt., Warsi J, Fezai M, Fores M, Elvira B, Lang F., Cell Physiol Biochem. January 1, 2015; 37 (6): 2454-63.

Inhibition of cardiac Kv1.5 potassium current by the anesthetic midazolam: mode of action., Vonderlin N, Fischer F, Zitron E, Seyler C, Scherer D, Thomas D, Katus HA, Scholz EP., Drug Des Devel Ther. November 7, 2014; 8 2263-71.        

Down-regulation of K⁺ channels by human parvovirus B19 capsid protein VP1., Ahmed M, Almilaji A, Munoz C, Elvira B, Shumilina E, Bock CT, Kandolf R, Lang F., Biochem Biophys Res Commun. August 8, 2014; 450 (4): 1396-401.

Transmembrane voltage potential of somatic cells controls oncogene-mediated tumorigenesis at long-range., Chernet BT, Levin M., Oncotarget. May 30, 2014; 5 (10): 3287-306.              

Isoenzyme-specific regulation of cardiac Kv1.5/Kvβ1.2 ion channel complex by protein kinase C: central role of PKCβII., Fischer F, Vonderlin N, Seyler C, Zitron E, Korkmaz S, Szabó G, Thomas D, Katus HA, Scholz EP., Naunyn Schmiedebergs Arch Pharmacol. May 1, 2014; 387 (5): 469-76.

Inhibition of cardiac Kv1.5 and Kv4.3 potassium channels by the class Ia anti-arrhythmic ajmaline: mode of action., Fischer F, Vonderlin N, Zitron E, Seyler C, Scherer D, Becker R, Katus HA, Scholz EP., Naunyn Schmiedebergs Arch Pharmacol. November 1, 2013; 386 (11): 991-9.

Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1., Aidery P, Kisselbach J, Schweizer PA, Becker R, Katus HA, Thomas D., Gene. December 10, 2012; 511 (1): 26-33.        

Inhibition of cardiac Kir2.1-2.3 channels by beta3 adrenoreceptor antagonist SR 59230A., Kulzer M, Seyler C, Welke F, Scherer D, Xynogalos P, Scholz EP, Thomas D, Becker R, Karle CA, Katus HA, Zitron E., Biochem Biophys Res Commun. July 27, 2012; 424 (2): 315-20.

18β-Glycyrrhetinic acid preferentially blocks late Na current generated by ΔKPQ Nav1.5 channels., Du YM, Xia CK, Zhao N, Dong Q, Lei M, Xia JH., Acta Pharmacol Sin. June 1, 2012; 33 (6): 752-60.            

Sigma-1 receptor alters the kinetics of Kv1.3 voltage gated potassium channels but not the sensitivity to receptor ligands., Kinoshita M, Matsuoka Y, Suzuki T, Mirrielees J, Yang J., Brain Res. May 3, 2012; 1452 1-9.

Activation of voltage gated K⁺ channel Kv1.5 by β-catenin., Munoz C, Tóvolli RH, Sopjani M, Alesutan I, Lam RS, Seebohm G, Föller M, Lang F., Biochem Biophys Res Commun. January 13, 2012; 417 (2): 692-6.

Downregulation of Kv1.5 K channels by the AMP-activated protein kinase., Mia S, Munoz C, Pakladok T, Siraskar G, Voelkl J, Alesutan I, Lang F., Cell Physiol Biochem. January 1, 2012; 30 (4): 1039-50.

Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway., Ferrer T, Cordero-Morales JF, Arias M, Ficker E, Medovoy D, Perozo E, Tristani-Firouzi M., J Biol Chem. November 11, 2011; 286 (45): 39091-9.

Extracellular potassium inhibits Kv7.1 potassium channels by stabilizing an inactivated state., Larsen AP, Steffensen AB, Grunnet M, Olesen SP., Biophys J. August 17, 2011; 101 (4): 818-27.

Four and a half LIM protein 1C (FHL1C): a binding partner for voltage-gated potassium channel K(v1.5)., Poparic I, Schreibmayer W, Schoser B, Desoye G, Gorischek A, Miedl H, Hochmeister S, Binder J, Quasthoff S, Wagner K, Windpassinger C, Malle E., PLoS One. January 1, 2011; 6 (10): e26524.            

Inhibition of voltage-gated K+ channels in dendritic cells by rapamycin., Tyan L, Sopjani M, Dërmaku-Sopjani M, Schmid E, Yang W, Thi Xuan N, Shumilina E, Lang F., Am J Physiol Cell Physiol. December 1, 2010; 299 (6): C1379-85.

Induction of vertebrate regeneration by a transient sodium current., Tseng AS, Beane WS, Lemire JM, Masi A, Levin M., J Neurosci. September 29, 2010; 30 (39): 13192-200.                    

Aconitine blocks HERG and Kv1.5 potassium channels., Li Y, Tu D, Xiao H, Du Y, Zou A, Liao Y, Dong S., J Ethnopharmacol. August 19, 2010; 131 (1): 187-95.

Fast and slow voltage sensor rearrangements during activation gating in Kv1.2 channels detected using tetramethylrhodamine fluorescence., Horne AJ, Peters CJ, Claydon TW, Fedida D., J Gen Physiol. July 1, 2010; 136 (1): 83-99.                      

Molecular determinants of Kv1.5 channel block by diphenyl phosphine oxide-1., Du YM, Zhang XX, Tu DN, Zhao N, Liu YJ, Xiao H, Sanguinetti MC, Zou A, Liao YH., J Mol Cell Cardiol. June 1, 2010; 48 (6): 1111-20.

Effect of NIP-142 on potassium channel alpha-subunits Kv1.5, Kv4.2 and Kv4.3, and mouse atrial repolarization., Tanaka H, Namekata I, Hamaguchi S, Kawamura T, Masuda H, Tanaka Y, Iida-Tanaka N, Takahara A., Biol Pharm Bull. January 1, 2010; 33 (1): 138-41.

Quercetin activates human Kv1.5 channels by a residue I502 in the S6 segment., Yang L, Ma JH, Zhang PH, Zou AR, Tu DN., Clin Exp Pharmacol Physiol. February 1, 2009; 36 (2): 154-61.

[Effects of telmisartan on voltage-gated Kv1.3 and Kv1.5 potassium channels expressed in Xenopus oocytes]., Li MW, Wang XP, Gao CY, Zou AR., Zhonghua Xin Xue Guan Bing Za Zhi. February 1, 2009; 37 (2): 165-8.

The C-terminal PDZ-binding motif in the Kv1.5 potassium channel governs its modulation by the Na+/H+ exchanger regulatory factor 2., Laufer J, Boehmer C, Jeyaraj S, Knuwer M, Klaus F, Lindner R, Palmada M, Lang F., Cell Physiol Biochem. January 1, 2009; 23 (1-3): 25-36.

Voltage clamp fluorimetry reveals a novel outer pore instability in a mammalian voltage-gated potassium channel., Vaid M, Claydon TW, Rezazadeh S, Fedida D., J Gen Physiol. August 1, 2008; 132 (2): 209-22.                      

Intrinsic electrostatic potential in the BK channel pore: role in determining single channel conductance and block., Carvacho I, Gonzalez W, Torres YP, Brauchi S, Alvarez O, Gonzalez-Nilo FD, Latorre R., J Gen Physiol. February 1, 2008; 131 (2): 147-61.                        

Modulation of the voltage-gated potassium channel Kv1.5 by the SGK1 protein kinase involves inhibition of channel ubiquitination., Boehmer C, Laufer J, Jeyaraj S, Klaus F, Lindner R, Lang F, Palmada M., Cell Physiol Biochem. January 1, 2008; 22 (5-6): 591-600.

Modulation of human Kv1.5 channel kinetics by N-cadherin., Koutsouki E, Lam RS, Seebohm G, Ureche ON, Ureche L, Baltaev R, Lang F., Biochem Biophys Res Commun. November 9, 2007; 363 (1): 18-23.

Kvbeta1.3 reduces the degree of stereoselective bupivacaine block of Kv1.5 channels., Arias C, Guizy M, David M, Marzian S, González T, Decher N, Valenzuela C., Anesthesiology. October 1, 2007; 107 (4): 641-51.

Association of Kv1.5 and Kv1.3 contributes to the major voltage-dependent K+ channel in macrophages., Vicente R, Escalada A, Villalonga N, Texidó L, Roura-Ferrer M, Martín-Satué M, López-Iglesias C, Soler C, Solsona C, Tamkun MM, Felipe A., J Biol Chem. December 8, 2006; 281 (49): 37675-85.

The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae., Abdel-Mottaleb Y, Clynen E, Jalali A, Bosmans F, Vatanpour H, Schoofs L, Tytgat J., FEBS Lett. November 13, 2006; 580 (26): 6254-8.

Binding site of a novel Kv1.5 blocker: a "foot in the door" against atrial fibrillation., Decher N, Kumar P, Gonzalez T, Pirard B, Sanguinetti MC., Mol Pharmacol. October 1, 2006; 70 (4): 1204-11.

Novel, potent inhibitors of human Kv1.5 K+ channels and ultrarapidly activating delayed rectifier potassium current., Lagrutta A, Wang J, Fermini B, Salata JJ., J Pharmacol Exp Ther. June 1, 2006; 317 (3): 1054-63.

Analysis of voltage-gated potassium channel beta1 subunits in the porcine neonatal ductus arteriosus., Hayama E, Imamura S, Wu C, Nakazawa M, Matsuoka R, Nakanishi T., Pediatr Res. February 1, 2006; 59 (2): 167-74.

Structural basis for competition between drug binding and Kvbeta 1.3 accessory subunit-induced N-type inactivation of Kv1.5 channels., Decher N, Kumar P, Gonzalez T, Renigunta V, Sanguinetti MC., Mol Pharmacol. October 1, 2005; 68 (4): 995-1005.

A single residue in the S6 transmembrane domain governs the differential flecainide sensitivity of voltage-gated potassium channels., Herrera D, Mamarbachi A, Simoes M, Parent L, Sauvé R, Wang Z, Nattel S., Mol Pharmacol. August 1, 2005; 68 (2): 305-16.

Effects of intracellular magnesium on Kv1.5 and Kv2.1 potassium channels., Tammaro P, Smirnov SV, Moran O., Eur Biophys J. February 1, 2005; 34 (1): 42-51.

Molecular basis for Kv1.5 channel block: conservation of drug binding sites among voltage-gated K+ channels., Decher N, Pirard B, Bundis F, Peukert S, Baringhaus KH, Busch AE, Steinmeyer K, Sanguinetti MC., J Biol Chem. January 2, 2004; 279 (1): 394-400.

Identification, synthesis, and activity of novel blockers of the voltage-gated potassium channel Kv1.5., Peukert S, Brendel J, Pirard B, Brüggemann A, Below P, Kleemann HW, Hemmerle H, Schmidt W., J Med Chem. February 13, 2003; 46 (4): 486-98.

Modulation of Kv1.5 currents by protein kinase A, tyrosine kinase, and protein tyrosine phosphatase requires an intact cytoskeleton., Mason HS, Latten MJ, Godoy LD, Horowitz B, Kenyon JL., Mol Pharmacol. February 1, 2002; 61 (2): 285-93.

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