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Summary Expression Phenotypes Gene Literature (74) GO Terms (4) Nucleotides (99) Proteins (42) Interactants (344) Wiki

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Selected cannabis terpenes synergize with THC to produce increased CB1 receptor activation., Raz N, Eyal AM, Zeitouni DB, Hen-Shoval D, Davidson EM, Danieli A, Tauber M, Ben-Chaim Y., Biochem Pharmacol. June 1, 2023; 212 115548.

Cell-autonomous and differential endocannabinoid signaling impacts the development of presynaptic retinal ganglion cell axon connectivity in vivo., Del Rio R, Serrano RG, Gomez E, Martinez JC, Edward MA, Santos RA, Diaz KS, Cohen-Cory S., Front Synaptic Neurosci. January 1, 2023; 15 1176864.

Direct Regulation of Hyperpolarization-Activated Cyclic-Nucleotide Gated (HCN1) Channels by Cannabinoids., Mayar S, Memarpoor-Yazdi M, Makky A, Eslami Sarokhalil R, D'Avanzo N., Front Mol Neurosci. April 6, 2022; 15 848540.                  

Voltage dependence of the cannabinoid CB1 receptor., Goldberger E, Tauber M, Ben-Chaim Y., Front Pharmacol. January 1, 2022; 13 1022275.                  

WIN55,212-2, a Dual Modulator of Cannabinoid Receptors and G Protein-Coupled Inward Rectifier Potassium Channels., An D, Peigneur S, Tytgat J., Biomedicines. April 28, 2021; 9 (5):               

Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation., Dobramysl U, Jarsch IK, Inoue Y, Shimo H, Richier B, Gadsby JR, Mason J, Szałapak A, Ioannou PS, Correia GP, Walrant A, Butler R, Hannezo E, Simons BD, Gallop JL., J Cell Biol. April 5, 2021; 220 (4):                                       

Primordial Germ Cell Specification in Vertebrate Embryos: Phylogenetic Distribution and Conserved Molecular Features of Preformation and Induction., Hansen CL, Pelegri F., Front Cell Dev Biol. January 1, 2021; 9 730332.              

Predation threats for a 24-h period activated the extension of axons in the brains of Xenopus tadpoles., Mori T, Kitani Y, Hatakeyama D, Machida K, Goto-Inoue N, Hayakawa S, Yamamoto N, Kashiwagi K, Kashiwagi A., Sci Rep. July 16, 2020; 10 (1): 11737.                    

Tug-of-war between actomyosin-driven antagonistic forces determines the positioning symmetry in cell-sized confinement., Sakamoto R, Tanabe M, Hiraiwa T, Suzuki K, Ishiwata S, Maeda YT, Miyazaki M., Nat Commun. June 15, 2020; 11 (1): 3063.            

Antennal ionotropic receptors IR64a1 and IR64a2 of the parasitoid wasp Microplitis mediator (Hymenoptera: Braconidate) collaboratively perceive habitat and host cues., Shan S, Wang SN, Song X, Khashaveh A, Lu ZY, Dhiloo KH, Li RJ, Gao XW, Zhang YJ., Insect Biochem Mol Biol. November 1, 2019; 114 103204.

Philanthotoxin Analogues That Selectively Inhibit Ganglionic Nicotinic Acetylcholine Receptors with Exceptional Potency., Kachel HS, Franzyk H, Mellor IR., J Med Chem. July 11, 2019; 62 (13): 6214-6222.

Regulation of actin assembly by PI(4,5)P2 and other inositol phospholipids: An update on possible mechanisms., Janmey PA, Bucki R, Radhakrishnan R., Biochem Biophys Res Commun. November 25, 2018; 506 (2): 307-314.

Nuclear ARP2/3 drives DNA break clustering for homology-directed repair., Schrank BR, Aparicio T, Li Y, Chang W, Chait BT, Gundersen GG, Gottesman ME, Gautier J., Nature. July 1, 2018; 559 (7712): 61-66.                              

Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature., Daste F, Walrant A, Holst MR, Gadsby JR, Mason J, Lee JE, Brook D, Mettlen M, Larsson E, Lee SF, Lundmark R, Gallop JL., J Cell Biol. November 6, 2017; 216 (11): 3745-3765.                

Block of nicotinic acetylcholine receptors by philanthotoxins is strongly dependent on their subunit composition., Kachel HS, Patel RN, Franzyk H, Mellor IR., Sci Rep. November 30, 2016; 6 38116.                

Cannabis in epilepsy: From clinical practice to basic research focusing on the possible role of cannabidivarin., Morano A, Cifelli P, Nencini P, Antonilli L, Fattouch J, Ruffolo G, Roseti C, Aronica E, Limatola C, Di Bonaventura C, Palma E, Giallonardo AT., Epilepsia Open. September 19, 2016; 1 (3-4): 145-151.    

Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES., Watson JR, Fox HM, Nietlispach D, Gallop JL, Owen D, Mott HR., J Biol Chem. June 24, 2016; 291 (26): 13875-90.                  

Ensemble-based virtual screening for cannabinoid-like potentiators of the human glycine receptor α1 for the treatment of pain., Wells MM, Tillman TS, Mowrey DD, Sun T, Xu Y, Xu Y, Tang P., J Med Chem. April 9, 2015; 58 (7): 2958-2966.

Regulation of ECM degradation and axon guidance by growth cone invadosomes., Santiago-Medina M, Gregus KA, Nichol RH, O'Toole SM, Gomez TM., Development. February 1, 2015; 142 (3): 486-96.                        

Triggering actin polymerization in Xenopus egg extracts from phosphoinositide-containing lipid bilayers., Walrant A, Saxton DS, Correia GP, Gallop JL., Methods Cell Biol. January 1, 2015; 128 125-47.

Intracellular transport based on actin polymerization., Khaitlina SY., Biochemistry (Mosc). September 1, 2014; 79 (9): 917-27.

Transcriptional regulation and nuclear reprogramming: roles of nuclear actin and actin-binding proteins., Miyamoto K, Gurdon JB., Cell Mol Life Sci. September 1, 2013; 70 (18): 3289-302.        

Efficient high-throughput sequencing of a laser microdissected chromosome arm., Seifertova E, Zimmerman LB, Gilchrist MJ, Macha J, Kubickova S, Cernohorska H, Zarsky V, Owens ND, Sesay AK, Tlapakova T, Krylov V., BMC Genomics. May 28, 2013; 14 357.        

Abelson interactor 1 (ABI1) and its interaction with Wiskott-Aldrich syndrome protein (wasp) are critical for proper eye formation in Xenopus embryos., Singh A, Winterbottom EF, Ji YJ, Hwang YS, Daar IO., J Biol Chem. May 17, 2013; 288 (20): 14135-14146.

Phosphoinositides and membrane curvature switch the mode of actin polymerization via selective recruitment of toca-1 and Snx9., Gallop JL, Walrant A, Cantley LC, Kirschner MW., Proc Natl Acad Sci U S A. April 30, 2013; 110 (18): 7193-8.

Deep ancestry of mammalian X chromosome revealed by comparison with the basal tetrapod Xenopus tropicalis., Mácha J, Teichmanová R, Sater AK, Wells DE, Tlapáková T, Zimmerman LB, Krylov V., BMC Genomics. July 16, 2012; 13 315.                  

Functional interactions between polydnavirus and host cellular innexins., Marziano NK, Hasegawa DK, Phelan P, Turnbull MW., J Virol. October 1, 2011; 85 (19): 10222-9.

Psychotropic and nonpsychotropic cannabis derivatives inhibit human 5-HT(3A) receptors through a receptor desensitization-dependent mechanism., Xiong W, Koo BN, Morton R, Zhang L., Neuroscience. June 16, 2011; 184 28-37.

The effect of Δ9-tetrahydrocannabinol on 5-HT3 receptors depends on the current density., Yang KH, Isaev D, Morales M, Petroianu G, Galadari S, Oz M., Neuroscience. November 24, 2010; 171 (1): 40-9.

Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: discovery of nanomolar, nonselective, and use-dependent antagonists., Frølund S, Bella A, Kristensen AS, Ziegler HL, Witt M, Olsen CA, Strømgaard K, Franzyk H, Jaroszewski JW., J Med Chem. October 28, 2010; 53 (20): 7441-51.

Self-assembly of filopodia-like structures on supported lipid bilayers., Lee K, Gallop JL, Rambani K, Kirschner MW., Science. September 10, 2010; 329 (5997): 1341-5.

The function of cortactin in the clustering of acetylcholine receptors at the vertebrate neuromuscular junction., Madhavan R, Gong ZL, Ma JJ, Chan AW, Peng HB., PLoS One. December 29, 2009; 4 (12): e8478.                

Development of the retinotectal system in the direct-developing frog Eleutherodactylus coqui in comparison with other anurans., Schlosser G., Front Zool. June 23, 2008; 5 9.              

pEg6, a spire family member, is a maternal gene encoding a vegetally localized mRNA in Xenopus embryos., Le Goff C, Laurent V, Le Bon K, Tanguy G, Couturier A, Le Goff X, Le Guellec R., Biol Cell. December 1, 2006; 98 (12): 697-708.

Delta9-tetrahydrocannabinol and endogenous cannabinoid anandamide directly potentiate the function of glycine receptors., Hejazi N, Zhou C, Oz M, Sun H, Ye JH, Zhang L., Mol Pharmacol. March 1, 2006; 69 (3): 991-7.

In vitro assembly of filopodia-like bundles., Vignjevic D, Peloquin J, Borisy GG., Methods Enzymol. January 1, 2006; 406 727-39.

In vitro reconstitution of cdc42-mediated actin assembly using purified components., Ho HY, Rohatgi R, Lebensohn AM, Kirschner MW., Methods Enzymol. January 1, 2006; 406 174-90.

Regulation of actin cytoskeleton architecture by Eps8 and Abi1., Roffers-Agarwal J, Xanthos JB, Miller JR., BMC Cell Biol. October 14, 2005; 6 36.                

The effects of conformational constraints and steric bulk in the amino acid moiety of philanthotoxins on AMPAR antagonism., Jørgensen MR, Olsen CA, Mellor IR, Usherwood PN, Witt M, Franzyk H, Jaroszewski JW., J Med Chem. January 13, 2005; 48 (1): 56-70.

Differential effects of endogenous and synthetic cannabinoids on alpha7-nicotinic acetylcholine receptor-mediated responses in Xenopus Oocytes., Oz M, Zhang L, Ravindran A, Morales M, Lupica CR., J Pharmacol Exp Ther. September 1, 2004; 310 (3): 1152-60.

Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation., Peterson JR, Bickford LC, Morgan D, Kim AS, Ouerfelli O, Kirschner MW, Rosen MK., Nat Struct Mol Biol. August 1, 2004; 11 (8): 747-55.

Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex., Ho HY, Rohatgi R, Lebensohn AM, Le Ma, Li J, Gygi SP, Kirschner MW., Cell. July 23, 2004; 118 (2): 203-16.

Clustering of Nck by a 12-residue Tir phosphopeptide is sufficient to trigger localized actin assembly., Campellone KG, Rankin S, Pawson T, Kirschner MW, Tipper DJ, Leong JM., J Cell Biol. February 2, 2004; 164 (3): 407-16.                

Reprogramming control of an allosteric signaling switch through modular recombination., Dueber JE, Yeh BJ, Chak K, Lim WA., Science. September 26, 2003; 301 (5641): 1904-8.

Cdc42-dependent actin polymerization during compensatory endocytosis in Xenopus eggs., Sokac AM, Co C, Taunton J, Bement W., Nat Cell Biol. August 1, 2003; 5 (8): 727-32.

Preparation and biological assessment of hydroxycinnamic acid amides of polyamines., Fixon-Owoo S, Levasseur F, Williams K, Sabado TN, Lowe M, Klose M, Joffre Mercier A, Fields P, Atkinson J., Phytochemistry. June 1, 2003; 63 (3): 315-34.

Solid-phase synthesis of polyamine toxin analogues: potent and selective antagonists of Ca2+-permeable AMPA receptors., Kromann H, Krikstolaityte S, Andersen AJ, Andersen K, Krogsgaard-Larsen P, Jaroszewski JW, Egebjerg J, Strømgaard K., J Med Chem. December 19, 2002; 45 (26): 5745-54.

Motility determinants in WASP family proteins., Yarar D, D'Alessio JA, Jeng RL, Welch MD., Mol Biol Cell. November 1, 2002; 13 (11): 4045-59.

Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes., Kanzaki M, Watson RT, Hou JC, Stamnes M, Saltiel AR, Pessin JE., Mol Biol Cell. July 1, 2002; 13 (7): 2334-46.

Accessory nuclei revisited: the translocation of snRNPs from the germinal vesicle to the periphery of the future embryo., Biliński SM, Kloc M., Chromosoma. March 1, 2002; 111 (1): 62-8.

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