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Summary Expression Phenotypes Gene Literature (72) GO Terms (6) Nucleotides (79) Proteins (40) Interactants (59) Wiki

Papers associated with kcna4

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KCNA4 deficiency leads to a syndrome of abnormal striatum, congenital cataract and intellectual disability., Kaya N, Alsagob M, D'Adamo MC, Al-Bakheet A, Hasan S, Muccioli M, Almutairi FB, Almass R, Aldosary M, Monies D, Mustafa OM, Alyounes B, Kenana R, Al-Zahrani J, Naim E, Binhumaid FS, Qari A, Almutairi F, Meyer B, Plageman TF, Pessia M, Colak D, Al-Owain M., J Med Genet. November 1, 2016; 53 (11): 786-792.

Regulation of Human Kv1.4 Channel Activity by the Antidepressant Metergoline., Yeom HD, Lee JH., Biol Pharm Bull. January 1, 2016; 39 (6): 1069-72.

Expression and function of a CP339,818-sensitive K⁺ current in a subpopulation of putative nociceptive neurons from adult mouse trigeminal ganglia., Sforna L, D'Adamo MC, Servettini I, Guglielmi L, Pessia M, Franciolini F, Catacuzzeno L., J Neurophysiol. April 1, 2015; 113 (7): 2653-65.

Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos., Chernet BT, Fields C, Levin M., Front Physiol. January 19, 2015; 5 519.                

S-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivation., Jerng HH, Pfaffinger PJ., PLoS One. January 1, 2014; 9 (3): e93315.                      

Analysis of the interaction of tarantula toxin Jingzhaotoxin-III (β-TRTX-Cj1α) with the voltage sensor of Kv2.1 uncovers the molecular basis for cross-activities on Kv2.1 and Nav1.5 channels., Tao H, Chen JJ, Xiao YC, Wu YY, Su HB, Li D, Wang HY, Deng MC, Wang MC, Liu ZH, Liang SP., Biochemistry. October 22, 2013; 52 (42): 7439-48.

Heme impairs the ball-and-chain inactivation of potassium channels., Sahoo N, Goradia N, Ohlenschläger O, Schönherr R, Friedrich M, Plass W, Kappl R, Hoshi T, Heinemann SH., Proc Natl Acad Sci U S A. October 15, 2013; 110 (42): E4036-44.

Comparison of the effects of antiarrhythmic drugs flecainide and verapamil on fKv1.4ΔN channel currents in Xenopus oocytes., Chen H, Zhang D, Chao SP, Ren JH, Xu L, Jiang XJ, Wang SM., Acta Pharmacol Sin. February 1, 2013; 34 (2): 221-30.            

Effects of L-type Calcium Channel Antagonists Verapamil and Diltiazem on fKv1.4ΔN Currents in Xenopus oocytes., Chen H, Zhang D, Hua Ren J, Ping Chao S., Iran J Pharm Res. January 1, 2013; 12 (4): 855-66.            

Interaction of the S6 proline hinge with N-type and C-type inactivation in Kv1.4 channels., Bett GC, Lis A, Guo H, Liu M, Zhou Q, Rasmusson RL., Biophys J. October 3, 2012; 103 (7): 1440-50.

Sigma-1 receptor alters the kinetics of Kv1.3 voltage gated potassium channels but not the sensitivity to receptor ligands., Kinoshita M, Matsuoka Y, Suzuki T, Mirrielees J, Yang J., Brain Res. May 3, 2012; 1452 1-9.

Effects of diltiazem and propafenone on the inactivation and recovery kinetics of fKv1.4 channel currents expressed in Xenopus oocytes., Zhang D, Wang SM, Chen H, Jiang XJ, Chao SP., Acta Pharmacol Sin. April 1, 2011; 32 (4): 465-77.                        

A model of the interaction between N-type and C-type inactivation in Kv1.4 channels., Bett GC, Dinga-Madou I, Zhou Q, Bondarenko VE, Rasmusson RL., Biophys J. January 5, 2011; 100 (1): 11-21.

Multiple intermediate states precede pore block during N-type inactivation of a voltage-gated potassium channel., Prince-Carter A, Pfaffinger PJ., J Gen Physiol. July 1, 2009; 134 (1): 15-34.                              

The effects of ginsenoside Rg(3) on human Kv1.4 channel currents without the N-terminal rapid inactivation domain., Lee JH, Lee JH, Choi SH, Lee BH, Shin TJ, Pyo MK, Hwang SH, Kim BR, Lee SM, Bae DH, Rhim H, Nah SY., Biol Pharm Bull. April 1, 2009; 32 (4): 614-8.

Regulation of antiarrhythmic drug propafenone effects on the c-type Kv1.4 potassium channel by PHo and K+., Wang Z, Wang S, Li J, Jiang X, Wang N., J Korean Med Sci. February 1, 2009; 24 (1): 84-91.              

Effect of amiodarone on Kv1.4 channel C-type inactivation: comparison of its effects with those induced by propafenone and verapamil., Xu L, Huang C, Chen J, Jiang X, Li X, Bett GC, Rasmusson RL, Wang S., Pharmazie. June 1, 2008; 63 (6): 475-9.

Ginsenoside Rg3 inhibits human Kv1.4 channel currents by interacting with the Lys531 residue., Lee JH, Lee JH, Lee BH, Choi SH, Yoon IS, Pyo MK, Shin TJ, Choi WS, Lim Y, Rhim H, Won KH, Lim YW, Choe H, Kim DH, Kim YI, Nah SY., Mol Pharmacol. March 1, 2008; 73 (3): 619-26.

Episodic ataxia type 1 mutation F184C alters Zn2+-induced modulation of the human K+ channel Kv1.4-Kv1.1/Kvbeta1.1., Imbrici P, D'Adamo MC, Cusimano A, Pessia M., Am J Physiol Cell Physiol. February 1, 2007; 292 (2): C778-87.

Episodic ataxia type 1 mutations in the KCNA1 gene impair the fast inactivation properties of the human potassium channels Kv1.4-1.1/Kvbeta1.1 and Kv1.4-1.1/Kvbeta1.2., Imbrici P, D'Adamo MC, Kullmann DM, Pessia M., Eur J Neurosci. December 1, 2006; 24 (11): 3073-83.

Effect of propafenone on Kv1.4 inactivation., Tian L, Jiang X, Rasmusson R, Wang S., J Physiol Biochem. December 1, 2006; 62 (4): 263-70.

DPP10 is an inactivation modulatory protein of Kv4.3 and Kv1.4., Li HL, Qu YJ, Lu YC, Bondarenko VE, Wang S, Skerrett IM, Morales MJ., Am J Physiol Cell Physiol. November 1, 2006; 291 (5): C966-76.

A single residue in the S6 transmembrane domain governs the differential flecainide sensitivity of voltage-gated potassium channels., Herrera D, Mamarbachi A, Simoes M, Parent L, Sauvé R, Wang Z, Nattel S., Mol Pharmacol. August 1, 2005; 68 (2): 305-16.

N type rapid inactivation in human Kv1.4 channels: functional role of a putative C-terminal helix., Sankaranarayanan K, Varshney A, Mathew MK., Mol Membr Biol. January 1, 2005; 22 (5): 389-400.

K+ activation of kir3.1/kir3.4 and kv1.4 K+ channels is regulated by extracellular charges., Claydon TW, Makary SY, Dibb KM, Boyett MR., Biophys J. October 1, 2004; 87 (4): 2407-18.

Disinactivation of N-type inactivation of voltage-gated K channels by an erbstatin analogue., Zhang ZH, Rhodes KJ, Childers WE, Argentieri TM, Wang Q., J Biol Chem. July 9, 2004; 279 (28): 29226-30.

Inactivation and recovery in Kv1.4 K+ channels: lipophilic interactions at the intracellular mouth of the pore., Bett GC, Rasmusson RL., J Physiol. April 1, 2004; 556 (Pt 1): 109-20.

Differential inhibition of transient outward currents of Kv1.4 and Kv4.3 by endothelin., Hagiwara K, Nunoki K, Ishii K, Abe T, Yanagisawa T., Biochem Biophys Res Commun. October 17, 2003; 310 (2): 634-40.

C-type inactivation involves a significant decrease in the intracellular aqueous pore volume of Kv1.4 K+ channels expressed in Xenopus oocytes., Jiang X, Bett GC, Li X, Bondarenko VE, Rasmusson RL., J Physiol. June 15, 2003; 549 (Pt 3): 683-95.

Kv1.4 channel block by quinidine: evidence for a drug-induced allosteric effect., Wang S, Morales MJ, Qu YJ, Bett GC, Strauss HC, Rasmusson RL., J Physiol. January 15, 2003; 546 (Pt 2): 387-401.

Regulation of N- and C-type inactivation of Kv1.4 by pHo and K+: evidence for transmembrane communication., Li X, Bett GC, Jiang X, Bondarenko VE, Morales MJ, Rasmusson RL., Am J Physiol Heart Circ Physiol. January 1, 2003; 284 (1): H71-80.

Expression of voltage-dependent potassium channels in the developing visual system of Xenopus laevis., Pollock NS, Ferguson SC, McFarlane S., J Comp Neurol. October 28, 2002; 452 (4): 381-91.                

Two pore residues mediate acidosis-induced enhancement of C-type inactivation of the Kv1.4 K(+) channel., Claydon TW, Boyett MR, Sivaprasadarao A, Orchard CH., Am J Physiol Cell Physiol. October 1, 2002; 283 (4): C1114-21.

Molecular determinants of intracellular pH modulation of human Kv1.4 N-type inactivation., Padanilam BJ, Lu T, Hoshi T, Padanilam BA, Shibata EF, Lee HC., Mol Pharmacol. July 1, 2002; 62 (1): 127-34.

Cumulative inactivation and the pore domain in the Kv1 channels., Shimizu Y, Kubo T, Furukawa Y., Pflugers Arch. March 1, 2002; 443 (5-6): 720-30.

A role for frequenin, a Ca2+-binding protein, as a regulator of Kv4 K+-currents., Nakamura TY, Pountney DJ, Ozaita A, Nandi S, Ueda S, Rudy B, Coetzee WA., Proc Natl Acad Sci U S A. October 23, 2001; 98 (22): 12808-13.

Cloning and expression of three K+ channel cDNAs from Xenopus muscle., Fry M, Paterno G, Moody-Corbett F., Brain Res Mol Brain Res. June 20, 2001; 90 (2): 135-48.          

Mutations in the Kv beta 2 binding site for NADPH and their effects on Kv1.4., Peri R, Wible BA, Brown AM., J Biol Chem. January 5, 2001; 276 (1): 738-41.

Inhibition of the K+ channel kv1.4 by acidosis: protonation of an extracellular histidine slows the recovery from N-type inactivation., Claydon TW, Boyett MR, Sivaprasadarao A, Ishii K, Owen JM, O'Beirne HA, Leach R, Komukai K, Orchard CH., J Physiol. July 15, 2000; 526 Pt 2 253-64.

Changes in the inactivation of rat Kv1.4 K(+) channels induced by varying the number of inactivation particles., Hashimoto Y, Nunoki K, Kudo H, Ishii K, Taira N, Yanagisawa T., J Biol Chem. March 31, 2000; 275 (13): 9358-62.

A functional spliced-variant of beta 2 subunit of Kv1 channels in C6 glioma cells and reactive astrocytes from rat lesioned cerebellum., Akhtar S, McIntosh P, Bryan-Sisneros A, Barratt L, Robertson B, Dolly JO., Biochemistry. December 21, 1999; 38 (51): 16984-92.

Inactivation gating of Kv4 potassium channels: molecular interactions involving the inner vestibule of the pore., Jerng HH, Shahidullah M, Covarrubias M., J Gen Physiol. May 1, 1999; 113 (5): 641-60.                        

Transplanting the N-terminus from Kv1.4 to Kv1.1 generates an inwardly rectifying K+ channel., Chanda B, Tiwari JK, Varshney A, Mathew MK., Neuroreport. February 5, 1999; 10 (2): 237-41.

Effect of Cd2+ on Kv4.2 and Kv1.4 expressed in Xenopus oocytes and on the transient outward currents in rat and rabbit ventricular myocytes., Wickenden AD, Tsushima RG, Losito VA, Kaprielian R, Backx PH., Cell Physiol Biochem. January 1, 1999; 9 (1): 11-28.

Separable effects of human Kvbeta1.2 N- and C-termini on inactivation and expression of human Kv1.4., Accili EA, Kuryshev YA, Wible BA, Brown AM., J Physiol. October 15, 1998; 512 ( Pt 2) 325-36.

Differential effects of S6 mutations on binding of quinidine and 4-aminopyridine to rat isoform of Kv1.4: common site but different factors in determining blockers' binding affinity., Zhang H, Zhu B, Yao JA, Tseng GN., J Pharmacol Exp Ther. October 1, 1998; 287 (1): 332-43.

Influence of outer pore residue K533 on the inhibition of Kv1.4 potassium channels by n-alkyl sulphate anions., MacDonald S, Elliott AA, Harrold JA, Elliott JR., Pflugers Arch. July 1, 1998; 436 (4): 623-6.

Toxin and subunit specificity of blocking affinity of three peptide toxins for heteromultimeric, voltage-gated potassium channels expressed in Xenopus oocytes., Hopkins WF., J Pharmacol Exp Ther. June 1, 1998; 285 (3): 1051-60.

Cyclosporin A selectively reduces the functional expression of Kir2.1 potassium channels in Xenopus oocytes., Chen H, Kubo Y, Hoshi T, Heinemann SH., FEBS Lett. February 6, 1998; 422 (3): 307-10.

Modification of rat brain Kv1.4 channel gating by association with accessory Kvbeta1.1 and beta2.1 subunits., McIntosh P, Southan AP, Akhtar S, Sidera C, Ushkaryov Y, Dolly JO, Robertson B., Pflugers Arch. December 1, 1997; 435 (1): 43-54.

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