Papers associated with tpx2

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	TPX2 promotes cell proliferation and migration via PLK1 in OC., Ma S, Rong X, Gao F, Yang Y, Wei L., Cancer Biomark. January 1, 2018; 22 (3): 443-451.
	MiR-29a-5p inhibits proliferation and invasion and induces apoptosis in endometrial carcinoma via targeting TPX2., Jiang T, Sui D, You D, Yao S, Zhang L, Wang Y, Zhao J, Zhang Y., Cell Cycle. January 1, 2018; 17 (10): 1268-1278.
	Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches., McIntyre PJ, Collins PM, Vrzal L, Birchall K, Arnold LH, Mpamhanga C, Coombs PJ, Burgess SG, Richards MW, Winter A, Veverka V, Delft FV, Merritt A, Bayliss R., ACS Chem Biol. November 17, 2017; 12 (11): 2906-2914.
	Regulation of mitotic spindle assembly factor NuMA by Importin-β., Chang CC, Huang TL, Shimamoto Y, Tsai SY, Hsia KC., J Cell Biol. November 6, 2017; 216 (11): 3453-3462.
	Targeting protein for Xenopus kinesin-like protein 2 knockdown enhances radiation sensitivity of human lung squamous carcinoma cell., Yang J, Gao F, Xu X, Wang Y, Zhu S., Clin Exp Pharmacol Physiol. October 1, 2017; 44 (10): 1060-1068.
	Effects of TPX2 gene on radiotherapy sensitization in breast cancer stem cells., Huang C, Han Z, Wu D., Oncol Lett. August 1, 2017; 14 (2): 1531-1535.
	Structural analysis of the role of TPX2 in branching microtubule nucleation., Alfaro-Aco R, Thawani A, Petry S., J Cell Biol. April 3, 2017; 216 (4): 983-997.
	TPX2 expression is associated with poor survival in gastric cancer., Tomii C, Inokuchi M, Takagi Y, Ishikawa T, Otsuki S, Uetake H, Kojima K, Kawano T., World J Surg Oncol. January 9, 2017; 15 (1): 14.
	How TPX2 helps microtubules branch out., Alfaro-Aco R, Petry S., Cell Cycle. January 1, 2017; 0.
	TPX2 promotes glioma cell proliferation and invasion via activation of the AKT signaling pathway., Gu JJ, Zhang JH, Chen HJ, Wang SS., Oncol Lett. December 1, 2016; 12 (6): 5015-5022.
	The C-terminal domain of TPX2 is made of alpha-helical tandem repeats., Sanchez-Pulido L, Perez L, Kuhn S, Vernos I, Andrade-Navarro MA., BMC Struct Biol. October 26, 2016; 16 (1): 17.
	Expression of microtubule-associated protein TPX2 in human gastric carcinoma and its prognostic significance., Shao C, Duan C, Wang J, Luan S, Gao Y, Jin D, Wang D, Li Y, Xu L., Cancer Cell Int. October 10, 2016; 16 79.
	The sequential activation of the mitotic microtubule assembly pathways favors bipolar spindle formation., Cavazza T, Malgaretti P, Vernos I., Mol Biol Cell. October 1, 2016; 27 (19): 2935-45.
	Overexpressed targeting protein for Xklp2 (TPX2) serves as a promising prognostic marker and therapeutic target for gastric cancer., Liang B, Zheng W, Fang L, Wu L, Zhou F, Yin X, Yu X, Zou Z., Cancer Biol Ther. August 2, 2016; 17 (8): 824-32.
	Mitotic noncoding RNA processing promotes kinetochore and spindle assembly in Xenopus., Grenfell AW, Heald R, Strzelecka M., J Cell Biol. July 18, 2016; 214 (2): 133-41.
	Xenopus LAP2β protein knockdown affects location of lamin B and nucleoporins and has effect on assembly of cell nucleus and cell viability., Dubińska-Magiera M, Chmielewska M, Kozioł K, Machowska M, Hutchison CJ, Goldberg MW, Rzepecki R., Protoplasma. May 1, 2016; 253 (3): 943-956.
	TPX2 in human clear cell renal carcinoma: Expression, function and prognostic significance., Chen QI, Cao B, Nan N, Wang YU, Zhai XU, Li Y, Chong T., Oncol Lett. May 1, 2016; 11 (5): 3515-3521.
	A versatile multivariate image analysis pipeline reveals features of Xenopus extract spindles., Grenfell AW, Strzelecka M, Crowder ME, Helmke KJ, Schlaitz AL, Heald R., J Cell Biol. April 11, 2016; 213 (1): 127-36.
	FSH Regulates mRNA Translation in Mouse Oocytes and Promotes Developmental Competence., Franciosi F, Manandhar S, Conti M., Endocrinology. February 1, 2016; 157 (2): 872-82.
	TPX2 promotes migration and invasion of human breast cancer cells., Yang Y, Li DP, Shen N, Yu XC, Li JB, Song Q, Zhang JH., Asian Pac J Trop Med. December 1, 2015; 8 (12): 1064-1070.
	An epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis., Meunier S, Shvedunova M, Van Nguyen N, Avila L, Vernos I, Akhtar A., Nat Commun. August 5, 2015; 6 7889.
	TPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux., Fu J, Bian M, Xin G, Deng Z, Luo J, Guo X, Chen H, Wang Y, Jiang Q, Zhang C., J Cell Biol. August 3, 2015; 210 (3): 373-83.
	TPX2 as a novel prognostic biomarker for hepatocellular carcinoma., Liu Q, Tu K, Zhang H, Zheng X, Yao Y, Liu Q., Hepatol Res. August 1, 2015; 45 (8): 906-18.
	GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules., Wei JH, Zhang ZC, Wynn RM, Seemann J., Cell. July 16, 2015; 162 (2): 287-99.
	Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly., Burgess SG, Peset I, Joseph N, Cavazza T, Vernos I, Pfuhl M, Gergely F, Bayliss R., PLoS Genet. July 1, 2015; 11 (7): e1005345.
	The Ran-GTP gradient spatially regulates XCTK2 in the spindle., Weaver LN, Ems-McClung SC, Chen SH, Yang G, Shaw SL, Walczak CE., Curr Biol. June 1, 2015; 25 (11): 1509-14.
	Phosphorylation of targeting protein for Xenopus kinesin-like protein 2 (TPX2) at threonine 72 in spindle assembly., Shim SY, Perez de Castro I, Neumayer G, Wang J, Park SK, Sanada K, Nguyen MD., J Biol Chem. April 3, 2015; 290 (14): 9122-34.
	Microtubule nucleation in mitosis by a RanGTP-dependent protein complex., Scrofani J, Sardon T, Meunier S, Vernos I., Curr Biol. January 19, 2015; 25 (2): 131-140.
	Positive Surgical Margin, HPV Persistence, and Expression of Both TPX2 and PD-L1 Are Associated with Persistence/Recurrence of Cervical Intraepithelial Neoplasia after Cervical Conization., Zhang H, Zhang T, You Z, Zhang Y., PLoS One. January 1, 2015; 10 (12): e0142868.
	Purification of nuclear localization signal-containing proteins and its application to investigation of the mechanisms of the cell division cycle., Christodoulou A, Yokoyama H., Small GTPases. January 1, 2015; 6 (1): 20-7.
	TPX2 is a prognostic marker and contributes to growth and metastasis of human hepatocellular carcinoma., Huang Y, Guo W, Kan H., Int J Mol Sci. October 9, 2014; 15 (10): 18148-61.
	TPX2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts., Helmke KJ, Heald R., J Cell Biol. August 4, 2014; 206 (3): 385-93.
	TPX2 knockdown suppressed hepatocellular carcinoma cell invasion via inactivating AKT signaling and inhibiting MMP2 and MMP9 expression., Liu Q, Yang P, Tu K, Zhang H, Zheng X, Yao Y, Liu Q., Chin J Cancer Res. August 1, 2014; 26 (4): 410-7.
	TPX2 overexpression in medullary thyroid carcinoma mediates TT cell proliferation., Yang X, Liu G, Xiao H, Yu F, Xiang X, Lu Y, Li W, Liu X, Li S, Shi Y., Pathol Oncol Res. July 1, 2014; 20 (3): 641-8.
	TPX2 regulates tumor growth in human cervical carcinoma cells., Jiang P, Shen K, Wang X, Song H, Yue Y, Liu T., Mol Med Rep. June 1, 2014; 9 (6): 2347-51.
	Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration., Bernis C, Swift-Taylor B, Nord M, Carmona S, Chook YM, Forbes DJ., Mol Biol Cell. April 1, 2014; 25 (7): 992-1009.
	The Prp19 complex directly functions in mitotic spindle assembly., Hofmann JC, Tegha-Dunghu J, Dräger S, Will CL, Lührmann R, Gruss OJ., PLoS One. September 3, 2013; 8 (9): e74851.
	The centriolar satellite protein SSX2IP promotes centrosome maturation., Bärenz F, Inoue D, Yokoyama H, Tegha-Dunghu J, Freiss S, Draeger S, Mayilo D, Cado I, Merker S, Klinger M, Hoeckendorf B, Pilz S, Hupfeld K, Steinbeisser H, Lorenz H, Ruppert T, Wittbrodt J, Gruss OJ., J Cell Biol. July 8, 2013; 202 (1): 81-95.
	Mitotic spindle scaling during Xenopus development by kif2a and importin α., Wilbur JD, Heald R., Elife. February 19, 2013; 2 e00290.
	Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2., Petry S, Groen AC, Ishihara K, Mitchison TJ, Vale RD., Cell. February 14, 2013; 152 (4): 768-77.
	Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation., Neumayer G, Helfricht A, Shim SY, Le HT, Lundin C, Belzil C, Chansard M, Yu Y, Lees-Miller SP, Gruss OJ, van Attikum H, Helleday T, Nguyen MD., J Biol Chem. December 7, 2012; 287 (50): 42206-22.
	On the molecular mechanisms of mitotic kinase activation., Bayliss R, Fry A, Haq T, Yeoh S., Open Biol. November 1, 2012; 2 (11): 120136.
	Crystal structure of human aurora B in complex with INCENP and VX-680., Elkins JM, Santaguida S, Musacchio A, Knapp S., J Med Chem. September 13, 2012; 55 (17): 7841-8.
	A novel role for TPX2 as a scaffold and co-activator protein of the Chromosomal Passenger Complex., Iyer J, Tsai MY., Cell Signal. August 1, 2012; 24 (8): 1677-89.
	A novel Aurora kinase A inhibitor MK-8745 predicts TPX2 as a therapeutic biomarker in non-Hodgkin lymphoma cell lines., Chowdhury A, Chowdhury S, Tsai MY., Leuk Lymphoma. March 1, 2012; 53 (3): 462-71.
	Activation of Aurora-A kinase by protein partner binding and phosphorylation are independent and synergistic., Dodson CA, Bayliss R., J Biol Chem. January 6, 2012; 287 (2): 1150-7.
	Mitotic spindle assembly around RCC1-coated beads in Xenopus egg extracts., Halpin D, Kalab P, Wang J, Weis K, Heald R., PLoS Biol. December 1, 2011; 9 (12): e1001225.
	[Establishment of a targeting protein for Xenopus kinesin-like protein 2 C' terminal SBP-3 x Flag tagged HCT 116 colorectal cancer cell model]., Huang ZB, Zhang ZY, Zhang XD, Miao SY, Wang LF, Du RL., Zhongguo Yi Xue Ke Xue Yuan Xue Bao. December 1, 2011; 33 (6): 624-8.
	Functional analysis of the microtubule-interacting transcriptome., Sharp JA, Plant JJ, Ohsumi TK, Borowsky M, Blower MD., Mol Biol Cell. November 1, 2011; 22 (22): 4312-23.
	Structural basis of specific binding between Aurora A and TPX2 by molecular dynamics simulations., Cheng Y, Zhang F, Chen Q, Gao J, Cui W, Ji M, Tung CH., J Chem Inf Model. October 24, 2011; 51 (10): 2626-35.

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