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Summary Expression Phenotypes Gene Literature (242) GO Terms (8) Nucleotides (225) Proteins (62) Interactants (1337) Wiki
XB-GENEPAGE-482929

Papers associated with smad2



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XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGFbeta proteins in Xenopus development., Birsoy B, Berg L, Williams PH, Smith JC, Wylie CC, Christian JL, Heasman J., Development. February 1, 2005; 132 (3): 591-602.                      

The ARID domain protein dril1 is necessary for TGF(beta) signaling in Xenopus embryos., Callery EM, Smith JC, Thomsen GH., Dev Biol. February 15, 2005; 278 (2): 542-59.                              

Functional specificity of the Xenopus T-domain protein Brachyury is conferred by its ability to interact with Smad1., Messenger NJ, Kabitschke C, Andrews R, Grimmer D, Núñez Miguel R, Blundell TL, Smith JC, Wardle FC., Dev Cell. April 1, 2005; 8 (4): 599-610.  

Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase., Dupont S, Zacchigna L, Cordenonsi M, Soligo S, Adorno M, Rugge M, Piccolo S., Cell. April 8, 2005; 121 (1): 87-99.                                  

Notch signaling modulates the nuclear localization of carboxy-terminal-phosphorylated smad2 and controls the competence of ectodermal cells for activin A., Abe T, Furue M, Kondow A, Matsuzaki K, Asashima M., Mech Dev. May 1, 2005; 122 (5): 671-80.            

Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1., Alliston T, Ko TC, Cao Y, Liang YY, Feng XH, Chang C, Derynck R., J Biol Chem. June 24, 2005; 280 (25): 24227-37.

Positive and negative regulation of the transforming growth factor beta/activin target gene goosecoid by the TFII-I family of transcription factors., Ku M, Sokol SY, Wu J, Tussie-Luna MI, Roy AL, Hata A., Mol Cell Biol. August 1, 2005; 25 (16): 7144-57.

BMP-3 is a novel inhibitor of both activin and BMP-4 signaling in Xenopus embryos., Gamer LW, Nove J, Levin M, Rosen V., Dev Biol. September 1, 2005; 285 (1): 156-68.              

The novel Smad-interacting protein Smicl regulates Chordin expression in the Xenopus embryo., Collart C, Verschueren K, Rana A, Smith JC, Huylebroeck D., Development. October 1, 2005; 132 (20): 4575-86.        

Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads., Schmierer B, Hill CS., Mol Cell Biol. November 1, 2005; 25 (22): 9845-58.

GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryos., Levine AJ, Brivanlou AH., Development. January 1, 2006; 133 (2): 209-16.            

Determination of the minimal domains of Mix.3/Mixer required for endoderm development., Doherty JR, Zhu H, Kuliyev E, Mead PE., Mech Dev. January 1, 2006; 123 (1): 56-66.                  

Vg 1 is an essential signaling molecule in Xenopus development., Birsoy B, Kofron M, Schaible K, Wylie C, Heasman J., Development. January 1, 2006; 133 (1): 15-20.    

Genomic profiling of mixer and Sox17beta targets during Xenopus endoderm development., Dickinson K, Leonard J, Baker JC., Dev Dyn. February 1, 2006; 235 (2): 368-81.                        

A novel Cripto-related protein reveals an essential role for EGF-CFCs in Nodal signalling in Xenopus embryos., Dorey K, Hill CS., Dev Biol. April 15, 2006; 292 (2): 303-16.  

Inhibitor-resistant type I receptors reveal specific requirements for TGF-beta signaling in vivo., Ho DM, Chan J, Bayliss P, Whitman M., Dev Biol. July 15, 2006; 295 (2): 730-42.            

Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling., Knockaert M, Sapkota G, Alarcón C, Massagué J, Brivanlou AH., Proc Natl Acad Sci U S A. August 8, 2006; 103 (32): 11940-5.

Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides., Rana AA, Collart C, Gilchrist MJ, Smith JC., PLoS Genet. November 17, 2006; 2 (11): e193.                                    

FoxD3 regulation of Nodal in the Spemann organizer is essential for Xenopus dorsal mesoderm development., Steiner AB, Engleka MJ, Lu Q, Piwarzyk EC, Yaklichkin S, Lefebvre JL, Walters JW, Pineda-Salgado L, Labosky PA, Kessler DS., Development. December 1, 2006; 133 (24): 4827-38.                    

Dullard promotes degradation and dephosphorylation of BMP receptors and is required for neural induction., Satow R, Kurisaki A, Chan TC, Hamazaki TS, Asashima M., Dev Cell. December 1, 2006; 11 (6): 763-74.              

Xenopus Dab2 is required for embryonic angiogenesis., Cheong SM, Choi SC, Han JK., BMC Dev Biol. December 19, 2006; 6 63.                  

Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways., Sapkota G, Knockaert M, Alarcón C, Montalvo E, Brivanlou AH, Massagué J., J Biol Chem. December 29, 2006; 281 (52): 40412-9.

Negative regulation of Activin/Nodal signaling by SRF during Xenopus gastrulation., Yun CH, Choi SC, Park E, Kim SJ, Chung AS, Lee HK, Lee HK, Lee HJ, Lee HJ, Han JK., Development. February 1, 2007; 134 (4): 769-77.              

Kinesin-mediated transport of Smad2 is required for signaling in response to TGF-beta ligands., Batut J, Howell M, Hill CS., Dev Cell. February 1, 2007; 12 (2): 261-74.  

Endofin acts as a Smad anchor for receptor activation in BMP signaling., Shi W, Chang C, Nie S, Xie S, Wan M, Cao X., J Cell Sci. April 1, 2007; 120 (Pt 7): 1216-24.

Tpt1 activates transcription of oct4 and nanog in transplanted somatic nuclei., Koziol MJ, Garrett N, Gurdon JB., Curr Biol. May 1, 2007; 17 (9): 801-7.        

The secreted EGF-Discoidin factor xDel1 is essential for dorsal development of the Xenopus embryo., Arakawa A, Matsuo-Takasaki M, Takai A, Inomata H, Matsumura M, Ikeya M, Takahashi K, Miyachi Y, Sasai N, Sasai Y., Dev Biol. June 1, 2007; 306 (1): 160-9.                    

The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning., Sander V, Reversade B, De Robertis EM., EMBO J. June 20, 2007; 26 (12): 2955-65.              

Interpretation of BMP signaling in early Xenopus development., Simeoni I, Gurdon JB., Dev Biol. August 1, 2007; 308 (1): 82-92.                  

Erbin inhibits transforming growth factor beta signaling through a novel Smad-interacting domain., Dai F, Chang C, Lin X, Dai P, Mei L, Feng XH., Mol Cell Biol. September 1, 2007; 27 (17): 6183-94.

XSUMO-1 is required for normal mesoderm induction and axis elongation during early Xenopus development., Yukita A, Michiue T, Danno H, Asashima M., Dev Dyn. October 1, 2007; 236 (10): 2757-66.    

Tsukushi modulates Xnr2, FGF and BMP signaling: regulation of Xenopus germ layer formation., Morris SA, Almeida AD, Tanaka H, Ohta K, Ohnuma S., PLoS One. October 10, 2007; 2 (10): e1004.                    

Regulation of the Xenopus Xsox17alpha(1) promoter by co-operating VegT and Sox17 sites., Howard L, Rex M, Clements D, Woodland HR., Dev Biol. October 15, 2007; 310 (2): 402-15.      

Neural induction requires continued suppression of both Smad1 and Smad2 signals during gastrulation., Chang C, Harland RM., Development. November 1, 2007; 134 (21): 3861-72.                

Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction., Pinho S, Niehrs C., Differentiation. December 1, 2007; 75 (10): 957-67.            

Nuclear accumulation of Smad complexes occurs only after the midblastula transition in Xenopus., Saka Y, Hagemann AI, Piepenburg O, Smith JC., Development. December 1, 2007; 134 (23): 4209-18.

Long-range action of Nodal requires interaction with GDF1., Tanaka C, Sakuma R, Nakamura T, Hamada H, Saijoh Y., Genes Dev. December 15, 2007; 21 (24): 3272-82.        

Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice., Pangas SA, Li X, Umans L, Zwijsen A, Huylebroeck D, Gutierrez C, Wang D, Martin JF, Jamin SP, Behringer RR, Robertson EJ, Matzuk MM., Mol Cell Biol. January 1, 2008; 28 (1): 248-57.

Unexpected activities of Smad7 in Xenopus mesodermal and neural induction., de Almeida I, Rolo A, Batut J, Hill C, Stern CD, Linker C., Mech Dev. January 1, 2008; 125 (5-6): 421-31.              

The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm., Spagnoli FM, Brivanlou AH., Development. February 1, 2008; 135 (3): 451-61.                                                    

Coordination of cell polarity during Xenopus gastrulation., Shindo A, Yamamoto TS, Ueno N., PLoS One. February 6, 2008; 3 (2): e1600.              

TGF-beta signaling is required for multiple processes during Xenopus tail regeneration., Ho DM, Whitman M., Dev Biol. March 1, 2008; 315 (1): 203-16.                  

Identification of a novel pool of extracellular pro-myostatin in skeletal muscle., Anderson SB, Goldberg AL, Whitman M., J Biol Chem. March 14, 2008; 283 (11): 7027-35.

Regulation of TGF-(beta) signalling by N-acetylgalactosaminyltransferase-like 1., Herr P, Korniychuk G, Yamamoto Y, Grubisic K, Oelgeschläger M., Development. May 1, 2008; 135 (10): 1813-22.                    

Ectodermal factor restricts mesoderm differentiation by inhibiting p53., Sasai N, Yakura R, Kamiya D, Nakazawa Y, Sasai Y., Cell. May 30, 2008; 133 (5): 878-90.                        

p53 regulation orchestrates the TGF-beta response., Piccolo S., Cell. May 30, 2008; 133 (5): 767-9.

Regulation of activin/nodal signaling by Rap2-directed receptor trafficking., Choi SC, Kim GH, Lee SJ, Park E, Yeo CY, Han JK., Dev Cell. July 1, 2008; 15 (1): 49-61.

Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling., Batut J, Schmierer B, Cao J, Raftery LA, Hill CS, Howell M., Development. September 1, 2008; 135 (17): 2927-37.  

Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formation., Cha SW, Tadjuidje E, Tao Q, Tao Q, Wylie C, Heasman J., Development. November 1, 2008; 135 (22): 3719-29.        

TGF-beta induces connexin43 gene expression in normal murine mammary gland epithelial cells via activation of p38 and PI3K/AKT signaling pathways., Tacheau C, Fontaine J, Loy J, Mauviel A, Verrecchia F., J Cell Physiol. December 1, 2008; 217 (3): 759-68.

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