Papers associated with slc12a3

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	The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride., Bazúa-Valenti S, Chávez-Canales M, Rojas-Vega L, González-Rodríguez X, Vázquez N, Rodríguez-Gama A, Argaiz ER, Melo Z, Plata C, Ellison DH, García-Valdés J, Hadchouel J, Gamba G., J Am Soc Nephrol. August 1, 2015; 26 (8): 1781-6.
	Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells., Aoto K, Sandell LL, Butler Tjaden NE, Yuen KC, Watt KE, Black BL, Durnin M, Trainor PA., Dev Biol. June 1, 2015; 402 (1): 3-16.
	The emergence of Pax7-expressing muscle stem cells during vertebrate head muscle development., Nogueira JM, Hawrot K, Sharpe C, Noble A, Wood WM, Jorge EC, Goldhamer DJ, Kardon G, Dietrich S., Front Aging Neurosci. May 19, 2015; 7 62.
	Regulation of HbPIP2;3, a Latex-Abundant Water Transporter, Is Associated with Latex Dilution and Yield in the Rubber Tree (Hevea brasiliensis Muell. Arg.)., An F, Zou Z, Cai X, Wang J, Rookes J, Lin W, Cahill D, Kong L., PLoS One. January 1, 2015; 10 (4): e0125595.
	WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4., Chávez-Canales M, Zhang C, Soukaseum C, Moreno E, Pacheco-Alvarez D, Vidal-Petiot E, Castañeda-Bueno M, Vázquez N, Rojas-Vega L, Meermeier NP, Rogers S, Jeunemaitre X, Yang CL, Ellison DH, Gamba G, Hadchouel J., Hypertension. November 1, 2014; 64 (5): 1047-53.
	Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3., McCormick JA, Yang CL, Zhang C, Davidge B, Blankenstein KI, Terker AS, Yarbrough B, Meermeier NP, Park HJ, McCully B, West M, Borschewski A, Himmerkus N, Bleich M, Bachmann S, Mutig K, Argaiz ER, Gamba G, Singer JD, Ellison DH., J Clin Invest. November 1, 2014; 124 (11): 4723-36.
	TACC3 is a microtubule plus end-tracking protein that promotes axon elongation and also regulates microtubule plus end dynamics in multiple embryonic cell types., Nwagbara BU, Faris AE, Bearce EA, Erdogan B, Ebbert PT, Evans MF, Rutherford EL, Enzenbacher TB, Lowery LA., Mol Biol Cell. November 1, 2014; 25 (21): 3350-62.
	Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts., Cerqueira DM, Tran U, Romaker D, Abreu JG, Wessely O., Dev Biol. October 1, 2014; 394 (1): 54-64.
	WNK3 abrogates the NEDD4-2-mediated inhibition of the renal Na+-Cl- cotransporter., Lagnaz D, Arroyo JP, Chávez-Canales M, Vázquez N, Rizzo F, Spirlí A, Debonneville A, Staub O, Gamba G., Am J Physiol Renal Physiol. August 1, 2014; 307 (3): F275-86.
	Six1 is a key regulator of the developmental and evolutionary architecture of sensory neurons in craniates., Yajima H, Suzuki M, Ochi H, Ikeda K, Sato S, Yamamura K, Ogino H, Ueno N, Kawakami K., BMC Biol. May 29, 2014; 12 40.
	MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney., Romaker D, Kumar V, Cerqueira DM, Cox RM, Wessely O., Proc Natl Acad Sci U S A. April 29, 2014; 111 (17): 6335-40.
	Protein phosphatase 1 inhibitor-1 deficiency reduces phosphorylation of renal NaCl cotransporter and causes arterial hypotension., Picard N, Trompf K, Yang CL, Miller RL, Carrel M, Loffing-Cueni D, Fenton RA, Ellison DH, Loffing J., J Am Soc Nephrol. March 1, 2014; 25 (3): 511-22.
	A novel N-terminal motif is responsible for the evolution of neural crest-specific gene-regulatory activity in vertebrate FoxD3., Ono H, Kozmik Z, Yu JK, Wada H., Dev Biol. January 15, 2014; 385 (2): 396-404.
	SPAK and OSR1 dependent down-regulation of murine renal outer medullary K channel ROMK1., Elvira B, Munoz C, Borras J, Chen H, Warsi J, Ajay SS, Shumilina E, Lang F., Kidney Blood Press Res. January 1, 2014; 39 (4): 353-60.
	Regulation of NKCC2 activity by inhibitory SPAK isoforms: KS-SPAK is a more potent inhibitor than SPAK2., Park HJ, Curry JN, McCormick JA., Am J Physiol Renal Physiol. December 15, 2013; 305 (12): F1687-96.
	Protein tyrosine phosphatase 4A3 (PTP4A3) is required for Xenopus laevis cranial neural crest migration in vivo., Maacha S, Planque N, Laurent C, Pegoraro C, Anezo O, Maczkowiak F, Monsoro-Burq AH, Saule S., PLoS One. December 9, 2013; 8 (12): e84717.
	Loss of Xenopus cadherin-11 leads to increased Wnt/β-catenin signaling and up-regulation of target genes c-myc and cyclin D1 in neural crest., Koehler A, Schlupf J, Schneider M, Kraft B, Winter C, Kashef J., Dev Biol. November 1, 2013; 383 (1): 132-45.
	The structure and development of Xenopus laevis cornea., Hu W, Haamedi N, Lee J, Kinoshita T, Ohnuma S., Exp Eye Res. November 1, 2013; 116 109-28.
	The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling., Wang F, Hu W, Xian J, Ohnuma S, Brenton JD., Dev Biol. July 1, 2013; 379 (1): 16-27.
	Expression and functional characterization of Xhmg-at-hook genes in Xenopus laevis., Macrì S, Sgarra R, Ros G, Maurizio E, Zammitti S, Milani O, Onorati M, Vignali R, Manfioletti G., PLoS One. July 1, 2013; 8 (7): e69866.
	Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation., Wu G, Peng JB., FEBS Lett. June 19, 2013; 587 (12): 1717-22.
	Efficient high-throughput sequencing of a laser microdissected chromosome arm., Seifertova E, Zimmerman LB, Gilchrist MJ, Macha J, Kubickova S, Cernohorska H, Zarsky V, Owens ND, Sesay AK, Tlapakova T, Krylov V., BMC Genomics. May 28, 2013; 14 357.
	Regulation of G-protein signaling via Gnas is required to regulate proximal tubular growth in the Xenopus pronephros., Zhang B, Romaker D, Ferrell N, Wessely O., Dev Biol. April 1, 2013; 376 (1): 31-42.
	Calponin 2 acts as an effector of noncanonical Wnt-mediated cell polarization during neural crest cell migration., Ulmer B, Hagenlocher C, Schmalholz S, Kurz S, Schweickert A, Kohl A, Roth L, Sela-Donenfeld D, Blum M., Cell Rep. March 28, 2013; 3 (3): 615-21.
	Insulin increases the functional activity of the renal NaCl cotransporter., Chávez-Canales M, Arroyo JP, Ko B, Vázquez N, Bautista R, Castañeda-Bueno M, Bobadilla NA, Hoover RS, Gamba G., J Hypertens. February 1, 2013; 31 (2): 303-11.
	Cell differentiation of pluripotent tissue sheets immobilized on supported membranes displaying cadherin-11., Körner A, Deichmann C, Rossetti FF, Köhler A, Konovalov OV, Wedlich D, Tanaka M., PLoS One. January 1, 2013; 8 (2): e54749.
	Characterization of a novel phosphorylation site in the sodium-chloride cotransporter, NCC., Rosenbaek LL, Assentoft M, Pedersen NB, MacAulay N, Fenton RA., J Physiol. December 1, 2012; 590 (23): 6121-39.
	Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest., Rada-Iglesias A, Bajpai R, Prescott S, Brugmann SA, Swigut T, Wysocka J., Cell Stem Cell. November 2, 2012; 11 (5): 633-48.
	Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process., Castañeda-Bueno M, Cervantes-Pérez LG, Vázquez N, Uribe N, Kantesaria S, Morla L, Bobadilla NA, Doucet A, Alessi DR, Gamba G., Proc Natl Acad Sci U S A. May 15, 2012; 109 (20): 7929-34.
	Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1., Bonnard C, Strobl AC, Shboul M, Lee H, Merriman B, Nelson SF, Ababneh OH, Uz E, Güran T, Kayserili H, Hamamy H, Reversade B., Nat Genet. May 13, 2012; 44 (6): 709-13.
	Novel NCC mutants and functional analysis in a new cohort of patients with Gitelman syndrome., Glaudemans B, Yntema HG, San-Cristobal P, Schoots J, Pfundt R, Kamsteeg EJ, Bindels RJ, Knoers NV, Hoenderop JG, Hoefsloot LH., Eur J Hum Genet. March 1, 2012; 20 (3): 263-70.
	A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo., Oi K, Sohara E, Rai T, Misawa M, Chiga M, Alessi DR, Sasaki S, Uchida S., Biol Open. February 15, 2012; 1 (2): 120-7.
	Hyaluronan is required for cranial neural crest cells migration and craniofacial development., Casini P, Nardi I, Ori M., Dev Dyn. February 1, 2012; 241 (2): 294-302.
	WNK3-SPAK interaction is required for the modulation of NCC and other members of the SLC12 family., Pacheco-Alvarez D, Vázquez N, Castañeda-Bueno M, de-Los-Heros P, Cortes-González C, Moreno E, Meade P, Bobadilla NA, Gamba G., Cell Physiol Biochem. January 1, 2012; 29 (1-2): 291-302.
	Similar effects of all WNK3 variants on SLC12 cotransporters., Cruz-Rangel S, Melo Z, Vázquez N, Meade P, Bobadilla NA, Pasantes-Morales H, Gamba G, Mercado A., Am J Physiol Cell Physiol. September 1, 2011; 301 (3): C601-8.
	Nedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway., Arroyo JP, Lagnaz D, Ronzaud C, Vázquez N, Ko BS, Moddes L, Ruffieux-Daidié D, Hausel P, Koesters R, Yang B, Stokes JB, Hoover RS, Gamba G, Staub O., J Am Soc Nephrol. September 1, 2011; 22 (9): 1707-19.
	WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters., Rinehart J, Vázquez N, Kahle KT, Hodson CA, Ring AM, Gulcicek EE, Louvi A, Bobadilla NA, Gamba G, Lifton RP., J Biol Chem. August 26, 2011; 286 (34): 30171-80.
	Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models., Liu Z, Xie J, Wu T, Truong T, Auchus RJ, Huang CL., Hum Mol Genet. March 1, 2011; 20 (5): 855-66.
	γ-Adducin stimulates the thiazide-sensitive NaCl cotransporter., Dimke H, San-Cristobal P, de Graaf M, Lenders JW, Deinum J, Hoenderop JG, Bindels RJ., J Am Soc Nephrol. March 1, 2011; 22 (3): 508-17.
	Rare mutations in SLC12A1 and SLC12A3 protect against hypertension by reducing the activity of renal salt cotransporters., Acuña R, Martínez-de-la-Maza L, Ponce-Coria J, Vázquez N, Ortal-Vite P, Pacheco-Alvarez D, Bobadilla NA, Gamba G., J Hypertens. March 1, 2011; 29 (3): 475-83.
	Cranial neural crest cells on the move: their roles in craniofacial development., Cordero DR, Brugmann S, Chu Y, Bajpai R, Jame M, Helms JA., Am J Med Genet A. February 1, 2011; 155A (2): 270-9.
	WNK3 is a putative chloride-sensing kinase., Pacheco-Alvarez D, Gamba G., Cell Physiol Biochem. January 1, 2011; 28 (6): 1123-34.
	Inversin relays Frizzled-8 signals to promote proximal pronephros development., Lienkamp S, Ganner A, Boehlke C, Schmidt T, Arnold SJ, Schäfer T, Romaker D, Schuler J, Hoff S, Powelske C, Eifler A, Krönig C, Bullerkotte A, Nitschke R, Kuehn EW, Kim E, Burkhardt H, Brox T, Ronneberger O, Gloy J, Walz G., Proc Natl Acad Sci U S A. November 23, 2010; 107 (47): 20388-93.
	A single residue in transmembrane domain 11 defines the different affinity for thiazides between the mammalian and flounder NaCl transporters., Castañeda-Bueno M, Vázquez N, Bustos-Jaimes I, Hernández D, Rodríguez-Lobato E, Pacheco-Alvarez D, Cariño-Cortés R, Moreno E, Bobadilla NA, Gamba G., Am J Physiol Renal Physiol. November 1, 2010; 299 (5): F1111-9.
	The activity of the thiazide-sensitive Na(+)-Cl(-) cotransporter is regulated by protein phosphatase PP4., Glover M, Mercier Zuber A, Figg N, O'Shaughnessy KM., Can J Physiol Pharmacol. October 1, 2010; 88 (10): 986-95.
	Effects of dietary K on cell-surface expression of renal ion channels and transporters., Frindt G, Palmer LG., Am J Physiol Renal Physiol. October 1, 2010; 299 (4): F890-7.
	A Single Amino Acid Substitution Makes WNK4 Susceptible to SB 203580 and SB 202190., Glover M, Sweeny C, Davis B, O'Shaughnessy KM., Open Med Chem J. September 3, 2010; 4 57-61.
	On the substrate recognition and negative regulation of SPAK, a kinase modulating Na+-K+-2Cl- cotransport activity., Gagnon KB, Delpire E., Am J Physiol Cell Physiol. September 1, 2010; 299 (3): C614-20.
	Serotonin 2B receptor signaling is required for craniofacial morphogenesis and jaw joint formation in Xenopus., Reisoli E, De Lucchini S, Nardi I, Ori M., Development. September 1, 2010; 137 (17): 2927-37.
	The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice., Leviel F, Hübner CA, Houillier P, Morla L, El Moghrabi S, Brideau G, Hassan H, Hatim H, Parker MD, Kurth I, Kougioumtzes A, Sinning A, Pech V, Riemondy KA, Miller RL, Hummler E, Shull GE, Aronson PS, Doucet A, Wall SM, Chambrey R, Eladari D., J Clin Invest. May 1, 2010; 120 (5): 1627-35.

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